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What is ezetimibe-simvastatin?

Ezetimibe and simvastatin are used in combination with dietary modification for the treatment of primary hypercholesterolemia (high cholesterol) and familial hypercholesterolemiais, a genetic disorder characterized by high cholesterol levels, specifically very high LDL levels.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
High Cholesterol 48 7 Efficacy_major Efficacy_moderate Efficacy_slight
Other 21 0
General health 10 1 Efficacy_slight
High triglycerides 1 1 Efficacy_major
Diagnostic assessment 1 0
Support heart health 1 0

See all 80 patients currently taking ezetimibe-simvastatin

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
0
Mild
2
None
8

Commonly reported side effects, conditions, and hospitalizations associated with ezetimibe-simvastatin

I was told that the medication would injure or add problems with my liver if I used it alot 1

Reported Dosages

  daily 10 mg daily 10 mg-10 mg daily 20 mg daily 10 mg-20 mg daily 10 mg-40 mg daily 40 mg daily 10 mg-80 mg daily 150 mg daily
  2 Number of Patients: 2 13 Number of Patients: 13 13 Number of Patients: 13 2 Number of Patients: 2 22 Number of Patients: 22 20 Number of Patients: 20 2 Number of Patients: 2 5 Number of Patients: 5 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking ezetimibe-simvastatin (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 7   Doctor's advice: 64%
Side effects too severe 2   Side effects too severe: 18%
Other 2   Other: 18%
Did not seem to work 1   Did not seem to work: 9%
Expense 1   Expense: 9%
Personal research 1   Personal research: 9%

See all 11 patients who’ve stopped taking ezetimibe-simvastatin

Currently Taking ezetimibe-simvastatin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking ezetimibe-simvastatin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of ezetimibe-simvastatin

Always
8 80%
Usually
1 10%
Sometimes
0 0%
Never
1 10%

Burden

Difficulty being on treatment

Burden of ezetimibe-simvastatin

Very
0 0%
Somewhat
1 10%
A little
1 10%
Not at all
8 80%

Cost

Paid out of pocket

Cost of ezetimibe-simvastatin

$200+
1 11%
$100-199
0 0%
$50-99
0 0%
$25-49
3 33%
< $25
5 56%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.