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Quinine Treatment Report

Brand Names: Qualaquin

What is Quinine? Quinine is an antimalarial agent. It is used off label for the prevention and treatment of nocturnal leg cramps. As of February 2007 the only quinine-containing product approved by the US Food and Drug Administration is Qualaquin.

See more information, including instructions, precautions, side effects, and interactions.


Reasons taken

109 patients in the community are taking or have taken Quinine.

Reason # Patients Percentage of patients
Stiffness/Spasticity 24 22%
Other 21 19%
Cramps 14 12%
Pain 9 8%
disease-related symptoms 6 5%
Fasciculations 4 3%
General health 3 2%
Convulsive spasms (clonus) 1 <1%
Leg cramps 1 <1%
Slow my ALS progress 1 <1%
Emotional lability 1 <1%

Other treatments patients are taking for disease-related symptoms include Baclofen, Tizanidine HCl, and Walking Stick/Cane.

Dosages

Based on the patients currently taking Quinine.

Top 10 (Show all)

All (Show Top 10)

  150mg as needed 200mg as needed 20mg as needed 260mg as needed 300mg as needed 324mg as needed 325mg as needed daily mg as needed 1 L daily 1 other daily 20 mg daily 30 mg daily 60 mg daily 150 mg daily 200 mg daily 250 mg daily 260 mg daily 284 mg daily 300 mg daily 324 mg daily 325 mg daily 350 mg daily 400 mg daily 648 mg daily 900 mg daily 3254 mg daily
  1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 6 Number of Patients: 6 1 Number of Patients: 1 11 Number of Patients: 11 7 Number of Patients: 7 6 Number of Patients: 6 2 Number of Patients: 2 1 Number of Patients: 1 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking Quinine or how long patients were taking Quinine before stopping.

Currently Taking Quinine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
1
4
1
11
15

Stopped Taking Quinine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
5
2
2
4
7
12
Why Patients Stopped Taking Quinine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 16 50% Other: 50%
Did not seem to work 5 16% Did not seem to work: 16%
Doctor's advice 4 13% Doctor's advice: 13%
Side effects too severe 4 13% Side effects too severe: 13%
Course of treatment ended 3 9% Course of treatment ended: 9%
Expense 2 6% Expense: 6%
Personal research 2 6% Personal research: 6%

Patient Reported Evaluations

Results from 6 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 100% 3

Other

Side-effects (as an overall problem)

Severe 33% 2
Moderate 0% 0
Mild 0% 0
None 67% 4

Top reported side-effects include: Nausea, Headaches, Blurred Vision

Summary results are based on 6 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 6)

  • ukiwi
    Sex: M
    Sensation: Moderate
    Overall: None
    Cognition: none
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: none
    Walking: moderate
  • ukiwi
  • by ukiwi
    Feb 18, 2009
  • EfficacyModerate
  • Side-effectsSevere
  • Stiffness/Spasticity
Advice/Tips
stopped taking, Tinitus severe - may sleeping difficult.

  • jr42
    Sex: M
    Mouth/throat: none
    Arms: moderate
    Chest: none
    Legs: mild
    Type: Lower Motor Neuron
  • jr42
  • by jr42
    Jan 22, 2009
  • EfficacyMajor
  • Side-effectsNone
  • Other
Advice/Tips
It's an effective drug to stop cramps.

See all evaluation results for Quinine

Report created on July 04, 2009.