What is calcitriol?
Calcitriol is vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.
Calcitriol is used to treat calcium deficiency with hypoparathyroidism (decreased functioning of the parathyroid glands) and metabolic bone disease in people with chronic kidney failure.
Calcitriol may also be used for other purposes not listed in this medication guide.
Do not use this medication if you have ever had an allergic reaction to vitamin D, or if you have:
- high levels of calcium in your blood (hypercalcemia); or
- high levels of vitamin D in your body (hypervitaminosis D).
Before taking calcitriol, tell your doctor about all of your medical conditions. You may not be able to take calcitriol, or you may need a dose adjustment or special tests to safely take this medication.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Calcitriol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not take other vitamin or mineral supplements unless your doctor has told you to.
Avoid using antacids without your doctor’s advice. Use only the specific type of antacid your doctor recommends. Antacids contain different minerals and some types can cause serious side effects if you take them together with calcitriol.
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Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include increased thirst or urination, uneven heart rate, weakness, behavior changes, bone pain, nausea, weight loss, decreased appetite, constipation, or a metallic taste in the mouth.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking calcitriol and call your doctor at once if you have any of these serious side effects:
- increased thirst,
- urinating more than usual;
- pain in your lower back;
- fast, slow, or uneven heart rate;
- weakness, drowsiness, changes in behavior;
- bone pain, muscle weakness, loss of height;
- nausea, constipation, loss of appetite, weight loss;
- slow growth (in a child taking calcitriol); or
- dry mouth or a metallic taste.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Before taking calcitriol, tell your doctor if you are taking any of the following medicines:
- digoxin (digitalis, Lanoxin, Lanoxicaps);
- cholestyramine (Questran, Prevalite);
- sevelamer (Renagel);
- ketoconazole (Nizoral);
- lanthanum (Fosrenol);
- seizure medication such as phenytoin (Dilantin) or phenobarbital (Solfoton);
- steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others; or
- a (water pill) diuretic such as hydrochlorothiazide (HCTZ, Esidrix, Hydrodiuril, Microzide,Oretic), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), and others.
This list is not complete and there may be other drugs that can interact with calcitriol. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Calcijex, Rocaltrol, calcitriol, and vitamin D3(1,25[OH]2)
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