What is insulin aspart-insulin aspart protamine?
Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart and insulin aspart protamine is a faster-acting form of insulin than regular human insulin.
Insulin aspart and insulin aspart protamine is used to treat type 1 (insulin-dependent) diabetes in adults.
Insulin aspart and insulin aspart protamine may also be used for other purposes not listed in this medication guide.
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Precautions
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Instructions
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Side Effects
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Interactions
Precautions
Do not use this medication if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).
Before using insulin aspart and insulin aspart protamine, tell your doctor if you have liver disease, kidney disease, or a nerve disorder.
This medication is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not change the brand of medication or syringes you are using without first talking to your doctor or pharmacist.
Avoid drinking alcohol. Your blood sugar may become dangerously low if you drink alcohol while using insulin aspart and insulin aspart protamine.
Do not expose insulin aspart and insulin aspart protamine to high heat. Throw the medication away if it becomes hotter than 98 degrees F.
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Instructions
Seek emergency medical attention if you think you have used too much of this medicine. An insulin overdose can cause life-threatening hypoglycemia.
Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure (convulsions), or coma.
Since insulin aspart and insulin aspart protamine is used before meals, you may not be on a timed dosing schedule. Whenever you use this medication, be sure to eat a meal right away. Do not use extra insulin aspart and insulin aspart protamine to make up a missed dose.
It is important to keep insulin aspart and insulin aspart protamine on hand at all times. Get your prescription refilled before you run out of medicine completely.
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Side Effects
Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out.
Call your doctor if you have a serious side effect such as:
- swelling in your hands or feet; or
- low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).
Hypoglycemia, or low blood sugar, is the most common side effect of insulin aspart and insulin aspart protamine. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (convulsions). Watch for signs of low blood sugar. Carry a piece of non-dietetic hard candy or glucose tablets with you in case you have low blood sugar.
Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin aspart and insulin aspart protamine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Interactions
Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use any of the following:
- albuterol (Proventil, Ventolin);
- clonidine (Catapres);
- reserpine;
- guanethidine (Ismelin); or
- beta-blockers such as atenolol (Tenormin), bisoprolol (Zebeta), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), timolol (Blocadren), and others.
There are many other medicines that can increase or decrease the effects of insulin aspart and insulin aspart protamine on lowering your blood sugar. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Other Names
NovoLog Mix 70/30, NovoLog Mix 70/30 FlexPen, Novolog Mix 70/30 PenFill, insulin aspart protamine-insulin aspart, and insulin aspart-insulin aspart protamine
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Disclaimer
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04