Vesicare Treatment Report

Category: Prescription Drugs

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Generic Name: Solifenacin

What is Vesicare?

An example of Vesicare

Vesicare is a brand name of the drug solifenacin, an anticholinergic medication used to treat overactive bladder. It works by relaxing the bladder muscles to prevent urgent, frequent, or uncontrolled urination. It comes as a tablet taken by mouth, usually once a day, with or without food.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
134 34 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
54 13 Efficacy_major Efficacy_moderate Efficacy_slight
28 8 Efficacy_major Efficacy_moderate Efficacy_slight
14 3 Efficacy_major Efficacy_slight
12 3 Efficacy_major Efficacy_moderate Efficacy_cant_tell
8 2 Efficacy_major Efficacy_slight

See all 239 patients currently taking Vesicare

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Reported Side Effects

Side effects as an overall problem

Severe
5
Moderate
10
Mild
18
None
37

Reported Dosages

  10mg as needed 5mg as needed daily 5 mg m,w,f 5 mg daily 10 mg daily 15 mg daily 20 mg daily
  1 Number of Patients: 1 3 Number of Patients: 3 3 Number of Patients: 3 1 Number of Patients: 1 113 Number of Patients: 113 104 Number of Patients: 104 2 Number of Patients: 2 9 Number of Patients: 9  

Reported Stop Reasons

Why Patients Stopped Taking Vesicare (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 21   Did not seem to work: 34%
Other 17   Other: 27%
Side effects too severe 14   Side effects too severe: 23%
Doctor's advice 10   Doctor's advice: 16%
Expense 6   Expense: 10%
Personal research 4   Personal research: 6%
Change in health plan coverage 3   Change in health plan coverage: 5%
Course of treatment ended 2   Course of treatment ended: 3%

See all 62 patients who’ve stopped taking Vesicare

Currently Taking Vesicare

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Vesicare

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Vesicare

Always
56 80%
Usually
11 16%
Sometimes
1 1%
Never
2 3%

Burden

Difficulty being on treatment

Burden of Vesicare

Very
2 3%
Somewhat
2 3%
A little
10 14%
Not at all
56 80%

Cost

Paid out of pocket

Cost of Vesicare

$200+
1 2%
$100-199
2 4%
$50-99
5 11%
$25-49
19 40%
< $25
20 43%

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15 patient evaluations for Vesicare

Purpose: Urinary problems (Started Apr 04, 2013)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Apr 22, 2013 5 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight SevereSevereSevereSevereSevere AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Apr 22, 2013
Advice & Tips
A different medication was suggested by my GP
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
  • freka
    Data Quality: 3 stars
    • Sex: Female
    • Age: 37y
    Condition: POTS 2 additional condition(s)
    Quality of Life:
    • Mental: None
    • Physical: Moderate
    I am: Very bad
  • 49727-thumb
  • See freka's full Vesicare history
Purpose: Bladder problems (Started Jul 01, 2007)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Oct 22, 2012 20 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
  • slowrambler
    Sex: M
    Data Quality: 1 star
    MS: 37 yrs
    Type: Secondary Progressive
    Relapse: Moderate
    Sensation: Severe
    Overall: Mild
    Cognition: none
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: none
    Walking: severe
  • Portrait_default_thumb
  • See slowrambler's full Vesicare history
Purpose: Bladder problems (Started Nov 19, 2010)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Sep 07, 2012 5 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
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What is solifenacin?

Solifenacin reduces muscle spasms of the bladder and urinary tract.

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Solifenacin may also be used for other purposes not listed in this medication guide.


Precautions

You should not use this medication if you are allergic to solifenacin, or have certain conditions. Be sure your doctor knows if you have:

  • untreated or uncontrolled narrow-angle glaucoma;
  • a stomach disorder causing delayed emptying; or
  • if you are unable to urinate.

Before using solifenacin, tell your doctor if you are allergic to any drugs, or if you have:

  • glaucoma;
  • liver disease;
  • kidney disease;
  • a blockage in your stomach or intestines; or
  • a history of "Long QT syndrome."

If you have any of these conditions, you may need a dose adjustment or special tests to safely take solifenacin.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether solifenacin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Solifenacin can decrease perspiration and you may be more prone to heat stroke.

Solifenacin can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include severe constipation or stomach pain, or urinating less than usual or not at all.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using solifenacin and call your doctor at once if you have any of these serious side effects:

  • hot, dry skin and extreme thirst;
  • severe stomach pain, or constipation for 3 days or longer;
  • pain or burning when you urinate; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dry mouth;
  • dry eyes, blurred vision;
  • mild constipation;
  • nausea, mild stomach pain or upset;
  • dizziness, tired feeling; or
  • fever, sore throat, body aches, or other flu symptoms.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

The following drugs can interact with solifenacin. Tell your doctor if you are using any of these:

  • arsenic trioxide (Trisenox);
  • chloroquine (Arelan) or halofantrine (Halfan);
  • droperidol (Inapsine);
  • HIV/AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), itraconazole (Sporanox), ketoconazole (Nizoral), pentamidine (NebuPent, Pentam), or troleandomycin (Tao);
  • narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose);
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), or thioridazine (Mellaril);
  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), quinidine (Quinidex, Quin-Release Quin-G), or sotalol (Betapace); or
  • an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.

This list is not complete and there may be other drugs that can interact with solifenacin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Other Names

VESIcare and solifenacin

Available Strengths & Dosages


Route Form Strength
oral tablet 5 mg
oral tablet 10 mg

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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