What is trospium?

Trospium relieves spasms of the bladder.

Trospium is used to treat overactive bladder and symptoms of urinary incontinence, frequency, and urgency.

Trospium may also be used for other purposes not listed in this medication guide.

Precautions

Do not take this medicine if you are allergic to trospium, or if you have

  • untreated or uncontrolled narrow-angle glaucoma;
  • a blockage in your digestive system; or
  • if you are unable to urinate.

Before taking trospium, tell your doctor if you are allergic to any drugs, or if you have:

  • glaucoma;
  • liver disease;
  • kidney disease;
  • a stomach or intestinal disorder such as ulcerative colitis;
  • a muscle disorder such as myasthenia gravis; or
  • an enlarged prostate.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether trospium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

Trospium can cause side effects that may impair your vision, thinking, or reactions. Be careful if you drive or do anything that requires you to be awake and able to see clearly.

Avoid using other medicines that make you sleepy (especially cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety). They can add to the side effects of trospium. Tell your doctor if you regularly use any of these medicines.

Avoid drinking alcohol. It can increase drowsiness caused by trospium.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include dry mouth, drowsiness, blurred vision, and dilated pupils.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using trospium and call your doctor at once if you urinate less than usual or not at all.

Less serious side effects may include:

  • dry mouth or throat;
  • dry eyes, blurred vision;
  • constipation;
  • stomach pain, bloating, gas;
  • drowsiness, or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Before taking trospium, tell your doctor if you are taking any of the following medicines:

  • atropine (Atreza, Sal-Tropine, and others);
  • dicyclomine (Bentyl);
  • glycopyrrolate (Robinul);
  • hyoscyamine (Anaspaz, Levbid, Levsin, Nulev, and others);
  • mepenzolate (Cantil);
  • metformin (Glucophage);
  • methscopolamine (Pamine);
  • morphine (Kadian, MS Contin, Oramorph);
  • procainamide (Procanbid, Pronestyl);
  • propantheline (Pro-Banthine);
  • scopolamine (Maldemar, Scopace, Transderm-Scop);
  • tenofovir (Viread); or
  • vancomycin (Vancocin).

This list is not complete and there may be other drugs that can interact with trospium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Regurin, Sanctura, trospium, and Sanctura XR

Available Strengths & Dosages


Route Form Strength
oral tablet 20 mg

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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