Do not take rasagiline if you have liver disease or an adrenal gland tumor (also called pheochromocytoma). Do not take rasagiline within 14 days before having surgery.
There are many other medicines that should not be taken together with rasagiline or serious medical problems could result. Tell your doctor about all the prescription and over-the-counter medications you use, including vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
While you are taking rasagiline and for 2 weeks after you stop taking it, you must not eat or drink certain foods and beverages that are high in tyramine, listed in the "What should I avoid while taking rasagiline?” section of this leaflet. Eating these foods while you are taking rasagiline can raise your blood pressure to dangerous levels. This may cause life-threatening symptoms such as sudden and severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, seizure (convulsions), and sudden numbness or weakness (especially on one side of the body). Call your doctor at once if you have any of these symptoms.
You should become very familiar with the list of foods you must avoid while taking rasagiline. Continue avoiding these foods for a full 14 days after you stop taking the medication.
Rasagiline can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.