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What is Methylprednisolone?

Methylprednisolone is a synthetic corticosteroid drug used primarily as an anti-inflammatory or immunosuppressant agent for diseases of hematologic, allergic, inflammatory, neoplastic, and autoimmune origin; also for graft-versus-host disease.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken	# of patients Efficacy	# of patients evaluated by
MS Multiple Sclerosis	253	45
Other	198	38
Stiffness/Spasticity	57	10
Pain	46	8
relapse	41	11
Fatigue	32	12
Optic neuritis (inflammation, optic nerve)	31	8
Vision	26	13
Numbness, tingling, pins & needles (paresthesia)	26	6
Sensation	26	6
disease-related symptoms	20	2
Mobility	19	6
Devic's Neuromyelitis Optica NMO	18	3
Relapse MS (exacerbation)	17	5
General health	16	4
Support another treatment	11	1
Balance problems	9	2
Inflammation, joints	7	1
Weakness in legs	6	1
Numbness	6	1
Don't know	5	1
Bladder problems	5	1
Excessive daytime sleepiness (somnolence)	4	1
Inflammation	4	0
Gait	3	0
Double vision (diplopia)	3	0
Heavy sensation in legs	3	0
Left leg weakness, pain, stiffness	2	0
Brain fog	2	0
flare-ups	2	1
Walking difficult without aid	2	1
Headaches	2	1
To slow relapse	2	2
Fibromyalgia flare	2	1
Sensory dysfunction, extreme	2	1
Brain lesions	2	1
Numbness in face	2	1
Numbness in legs	2	0
Asthma	2	1
Back pain	2	1
Tingling	2	1
Help with symptoms	2	2
Lesions	1	0
vision disturbance (R eye)	1	0
Numbness in right foot	1	0
Chest pain	1	0
Borderline Systemic Lupus	1	1
Burning sensation all around torso-like a tight belt	1	0
Speech problems	1	0
Pins and needles sensation Right Leg	1	0
right foot pain in various spots	1	0
Vision changes/problems	1	0
Arm tingle	1	1
Staggering walk	1	0
improve walking ability & fatigue	1	1
Numbness in legs, feet, arms and hands	1	0
Lesson symptoms	1	1
Flair Up	1	0
loss of balance, falling	1	0
Numbness in feet	1	0
Cauda Equina Syndrome (CES) due to MS	1	0
Burning, aching, muscle weakness	1	0
help stop an exacerbation	1	1
relpse	1	0
heel spur	1	0
Treat an exacerbation	1	0
speach	1	0
Keeping symptoms at bay.	1	1
taper after IV	1	0
Speech ataxia-problems coordinating speech	1	1
complete left side weakness	1	0
reduce symptom severity	1	0
Shingles (herpes zoster)	1	0
Treat Optic Neuritis	1	1
Drenching sweats during flares	1	0
Pain and weakness in hands and arms from the elbows down	1	0
difficulty focusing	1	1
old symptoms	1	1
Numbness in back	1	0
Numbness in hands	1	0
Numbness in right hand	1	1
Swelling	1	0
Lung Congestion	1	0
Pain, severe itching and weakness in right hand	1	0
reduce leg pain and stiffness	1	1
imbalance, fatigue	1	1
Pins and needle in feet & legs	1	0
autoimune reduction	1	1
Difficulty with concentration	1	1
Rash/skin problems	1	0
Facial pain	1	0
Migraine	1	0
starting a relapse	1	0
Muscle spasms	1	0
Stiffness in legs	1	1
Dizzyness/Vertigo	1	1
Cognition	1	0
eczema flare	1	1
Leg pain (left)	1	1
Leg pain (both)	1	0
Swallowing	1	1
reduce inflamation	1	1
Sinus and fluid in ears	1	0
Blurry vision	1	1
cluster/migraine headache	1	0
Head pain	1	1
relapse of optic neuritis	1	0
I walk much better when I receive these infusions once a month	1	0
possible relaspe	1	0
Stumbling walk	1	0
supplements	1	0
IV steriods not powder 1,000 mg over 2 days	1	0
couldn't feel or use left foot or arm, crawling sensations on left side of neck and head	1	0
Paresthesia	1	1
Loss of use of right side	1	0
Plantar fasciitis (painful foot)	1	0
slow my MS progress, spasticity of my hand, fatigue, overcome my sight problem, weakness of my lower limbs especially my right leg and incontinensia uri	1	0
helps symptoms	1	0
low energy	1	0
Numbness in right arm	1	1
makes me stronger	1	0
Dizziness	1	0
Vision loss	1	0
Walking problems	1	0
syncope	1	0
energy and control pain	1	0
trying to reduce symptoms	1	0
MS relapse	1	1
Eye floaters	1	0
energy,pain,allergies,stiff joints,adrenal hormones low	1	0
Acute Relapse	1	0
Stiffness	1	0
Numbness in hands, arms, legs, and waist	1	0
Hives	1	1
Relapse/Maintainence	1	1
doctor ordered (no symptoms at time of treatment)	1	0

See all 136 reasons taken ▼

See all 340 patients currently taking Methylprednisolone

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe	29	16%
Moderate	64	36%
Mild	45	26%
None	38	22%

Most commonly reported side effects

Taste changed	44	35%
Sleeplessness	40	32%
Weight gain	36	29%
Insomnia	30	24%
Metallic taste in mouth	30	24%
Increased appetite	29	23%
jumpy feeling	27	22%
Restlessness	21	17%
Flush	21	17%
Heartburn (reflux)	21	17%
Anxiety	15	12%
Headaches	13	10%
affected eyes	12	10%
Nausea	12	10%
metalic taste	11	9%
roid affect	9	7%
come down	8	6%
Hair loss (alopecia)	7	6%
Thrush	7	6%
Elevated blood sugar (glucose)	6	5%
High blood pressure (Hypertension)	4	3%
Racing Heart	4	3%
Fatigue	3	2%
low heart rate	3	2%
Unable to sleep	3	2%
Irritability	3	2%
thirst	2	2%
Anger	2	2%
Sleep problems	2	2%
Sleepiness	2	2%
manic feelings	2	2%
low potassium	2	2%
Light sensitivity (photophobia)	2	2%
Spinning dizziness	1	1%
Vivid dreams	1	1%
uneasy feeling	1	1%
headache	1	1%
heightened energy	1	1%
Lightheadedness	1	1%
hallucinations (visual distortion)	1	1%
Bruiselike feeling under skin	1	1%
Swelling in hands	1	1%
Joint pain	1	1%
Moon Face	1	1%
Red face	1	1%
Swollen feet	1	1%
Leg pain (both)	1	1%
Hearing problems	1	1%
joint pain in legs	1	1%
Emotional lability	1	1%
Water retention	1	1%
Hyperactive	1	1%
Shakiness	1	1%
buzzy feeling	1	1%
Heart racing (tachycardia)	1	1%
swelling ankles & feet	1	1%
legs very heavy	1	1%
symptoms get worse whem I'm on IVSM	1	1%
Paranoid	1	1%
Pins and needles	1	1%
Dizziness	1	1%
Pain	1	1%
fluxuating energy, high & low	1	1%
Loss of appetite	1	1%
Stomach pain	1	1%
Fluid retention weight gain	1	1%
pain and weak body	1	1%
Always Hungry	1	1%
Jitteriness	1	1%
rapid weight loss	1	1%
kidney damage	1	1%
Numbness	1	1%
burning feet	1	1%
Visual Disturbanc; blurriness	1	1%
hand and face swelling	1	1%
Increased Hunger	1	1%
Gastrointestinal Reflux Disease (GERD)	1	1%
Bone Pain	1	1%
immune system weakened	1	1%
Shortness of breath	1	1%
Motion sickness	1	1%
Hives	1	1%
racing heart beat	1	1%
Brain fog	1	1%
no energy	1	1%
Chest pain	1	1%
hard to focus	1	1%
teeth	1	1%
Upset stomach	1	1%
emotional instability	1	1%
heartburn	1	1%
Raised Blood Sugar Levels	1	1%
Sweating excessive	1	1%
Pain throughout body	1	1%
Muscle aches	1	1%
Depression	1	1%
MS hug in chest	1	1%
Acid reflux (GER gastroesophageal reflux)	1	1%
Lethargy	1	1%
Eye sensitivity to bright light / sun	1	1%
Abdominal pain	1	1%
anger/anxiety	1	1%
facial flushing	1	1%

Mild
Moderate
Severe

See all 103 reported side effects ▼

Dosages

Top 10 dosages based on patients currently taking Methylprednisolone. See all 98 dosages ►

1000 as needed	1000 mg as needed	1000mg as needed	1 g as needed	1g as needed	1g monthly	1hours as needed	1mg as needed	1other as needed	20mg as needed	2 1g as needed	24mg as needed	250mg as needed	2g as needed	2 mg as needed	32mg as needed	3g as needed	40mg as needed	4 80mg/mL as needed	4 mg all the time (24/7)	4mg as needed	500mg as needed	50mg as needed	5 4mg as needed	5mg as needed	6 2mg as needed	80 mg as needed	8 500mg as needed	as needed	daily	g as needed	mg as needed	monthly	3 g yearly	6 g yearly	1 g monthly	1 mEq/L monthly	1 monthly	1 other monthly	2 hr monthly	1 g every other week	1 mg every other week	3 g monthly	40 mg yearly	4 mg monthly	1 g weekly	64 mg yearly	2 mg weekly	4 mg weekly	24 mg monthly	1 daily	1 g daily	1 g one time	1 hr one time	40 mg monthly	60 mg monthly	2 hr daily	2 mg daily	84 mg monthly	3 g daily	3 g one time	3 hr one time	100 mg monthly	4 g daily	4 mg daily	125 mg monthly	5 g one time	6 mg daily	7.5 daily	8 mg daily	10 g daily	12 mg daily	16 mg daily	500 mg monthly	20 mg daily	20 mg one time	24 mg daily	1000 mg monthly	1024 mg monthly	500 mg every other week	40 mg daily	1500 mg monthly	50 intl units one time	50 mg daily	1000 mg every other week	500 mg weekly	80 mg daily	84 mg daily	96 mg daily	100 mg daily	1000 mg weekly	250 mg daily	500 mg daily	1000 daily	1000 g daily	1000 mcg daily	1000 mg daily	2000 mg daily
3	1	14	2	22	1	1	1	1	1	1	1	1	1	1	1	1	1	1	2	5	3	1	1	1	1	1	1	11	18	1	2	7	1	1	30	1	1	2	1	2	1	1	1	1	1	1	1	1	1	1	31	4	1	1	1	1	2	1	3	1	1	1	1	17	4	1	1	1	2	1	1	3	3	1	1	1	13	1	1	1	2	1	1	1	1	2	1	1	1	1	2	8	1	3	1	26	1

Stop Reasons

Why Patients Stopped Taking Methylprednisolone (multiple reasons could be selected)
Reason	# Patients	Percentage of patients
Course of treatment ended	484	82%
Doctor's advice	53	9%
Did not seem to work	40	7%
Side effects too severe	31	5%
Other	26	4%
Not indicated	24	4%
Personal research	3	1%
Change in health plan coverage	1	0%

See all 578 patients who’ve stopped taking Methylprednisolone

Duration See details about how long patients take this treatment ▼

Currently Taking Methylprednisolone

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
9	11	23	25	38	51

Stopped Taking Methylprednisolone

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
379	36	24	38	36	81

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always	155	88%
Usually	12	7%
Sometimes	5	3%
Never	4	2%

Burden

Difficulty being on treatment

Very	13	7%
Somewhat	49	28%
A little	41	23%
Not at all	73	41%

Cost

Paid out of pocket

$200+	10	6%
$100-199	7	4%
$50-99	9	5%
$25-49	1	1%
< $25	68	39%

See more information, including instructions, precautions, side effects, and interactions.

Patient Evaluations

See all 176 patient evaluations

ArleneDwithMS

Sex: F

Sensation: Moderate

Overall: Moderate

Cognition: moderate

Vision: moderate

Speech: moderate

Swallowing: moderate

Upper limb: moderate

Walking: moderate

See profile
ArleneDwithMS

1 g daily

since Oct 23, 2009
Efficacy Can't tell for relapse
Side Effects Mild
Advice/Tips My Solu-Medrol IV's are being taken at home. A critical nurse came in to my house, explained it all to me and put in the IV in my left hand on the side of my... See full evaluation

Farmer in WI

Sex: F

Sensation: Moderate

Overall: Moderate

Cognition: moderate

Vision: moderate

Speech: moderate

Swallowing: moderate

Upper limb: moderate

Walking: moderate

See profile
Farmer in WI

500 mg daily

since Aug 17, 2009
Efficacy Can't tell for help stop an exacerbation
Side Effects Severe
Advice/Tips Give it a chance. It affects each of us differently and helps each situation differently. See full evaluation

Flowers

Sex: F

Sensation: Severe

Overall: Severe

Cognition: severe

Vision: moderate

Speech: moderate

Swallowing: moderate

Upper limb: moderate

Walking: moderate

See profile
Flowers

since Aug 21, 2008
Efficacy Major for MS Multiple Sclerosis
Side Effects Severe
Advice/Tips I know alot of people aren't into this treatment, but it's done wonders for me in the past and I will continue with it if I need to. See full evaluation

See all 176 patient evaluations

Forum

See 10 topics tagged with Methylprednisolone

There are 345 posts in our forum about Methylprednisolone. Join now and see what people are saying.

Report created on February 09, 2010.

1000 as needed	1000 mg as needed	1000mg as needed	1 g as needed	1g as needed	1g monthly	1hours as needed	1mg as needed	1other as needed	20mg as needed	2 1g as needed	24mg as needed	250mg as needed	2g as needed	2 mg as needed	32mg as needed	3g as needed	40mg as needed	4 80mg/mL as needed	4 mg all the time (24/7)	4mg as needed	500mg as needed	50mg as needed	5 4mg as needed	5mg as needed	6 2mg as needed	80 mg as needed	8 500mg as needed	as needed	daily	g as needed	mg as needed	monthly	3 g yearly	6 g yearly	1 g monthly	1 mEq/L monthly	1 monthly	1 other monthly	2 hr monthly	1 g every other week	1 mg every other week	3 g monthly	40 mg yearly	4 mg monthly	1 g weekly	64 mg yearly	2 mg weekly	4 mg weekly	24 mg monthly	1 daily	1 g daily	1 g one time	1 hr one time	40 mg monthly	60 mg monthly	2 hr daily	2 mg daily	84 mg monthly	3 g daily	3 g one time	3 hr one time	100 mg monthly	4 g daily	4 mg daily	125 mg monthly	5 g one time	6 mg daily	7.5 daily	8 mg daily	10 g daily	12 mg daily	16 mg daily	500 mg monthly	20 mg daily	20 mg one time	24 mg daily	1000 mg monthly	1024 mg monthly	500 mg every other week	40 mg daily	1500 mg monthly	50 intl units one time	50 mg daily	1000 mg every other week	500 mg weekly	80 mg daily	84 mg daily	96 mg daily	100 mg daily	1000 mg weekly	250 mg daily	500 mg daily	1000 daily	1000 g daily	1000 mcg daily	1000 mg daily	2000 mg daily
3	1	14	2	22	1	1	1	1	1	1	1	1	1	1	1	1	1	1	2	5	3	1	1	1	1	1	1	11	18	1	2	7	1	1	30	1	1	2	1	2	1	1	1	1	1	1	1	1	1	1	31	4	1	1	1	1	2	1	3	1	1	1	1	17	4	1	1	1	2	1	1	3	3	1	1	1	13	1	1	1	2	1	1	1	1	2	1	1	1	1	2	8	1	3	1	26	1

1000 as needed	1000 mg as needed	1000mg as needed	1 g as needed	1g as needed	1g monthly	1hours as needed	1mg as needed	1other as needed	20mg as needed	2 1g as needed	24mg as needed	250mg as needed	2g as needed	2 mg as needed	32mg as needed	3g as needed	40mg as needed	4 80mg/mL as needed	4 mg all the time (24/7)	4mg as needed	500mg as needed	50mg as needed	5 4mg as needed	5mg as needed	6 2mg as needed	80 mg as needed	8 500mg as needed	as needed	daily	g as needed	mg as needed	monthly	3 g yearly	6 g yearly	1 g monthly	1 mEq/L monthly	1 monthly	1 other monthly	2 hr monthly	1 g every other week	1 mg every other week	3 g monthly	40 mg yearly	4 mg monthly	1 g weekly	64 mg yearly	2 mg weekly	4 mg weekly	24 mg monthly	1 daily	1 g daily	1 g one time	1 hr one time	40 mg monthly	60 mg monthly	2 hr daily	2 mg daily	84 mg monthly	3 g daily	3 g one time	3 hr one time	100 mg monthly	4 g daily	4 mg daily	125 mg monthly	5 g one time	6 mg daily	7.5 daily	8 mg daily	10 g daily	12 mg daily	16 mg daily	500 mg monthly	20 mg daily	20 mg one time	24 mg daily	1000 mg monthly	1024 mg monthly	500 mg every other week	40 mg daily	1500 mg monthly	50 intl units one time	50 mg daily	1000 mg every other week	500 mg weekly	80 mg daily	84 mg daily	96 mg daily	100 mg daily	1000 mg weekly	250 mg daily	500 mg daily	1000 daily	1000 g daily	1000 mcg daily	1000 mg daily	2000 mg daily
3	1	14	2	22	1	1	1	1	1	1	1	1	1	1	1	1	1	1	2	5	3	1	1	1	1	1	1	11	18	1	2	7	1	1	30	1	1	2	1	2	1	1	1	1	1	1	1	1	1	1	31	4	1	1	1	1	2	1	3	1	1	1	1	17	4	1	1	1	2	1	1	3	3	1	1	1	13	1	1	1	2	1	1	1	1	2	1	1	1	1	2	8	1	3	1	26	1

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Methylprednisolone Treatment Report