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What is naratriptan?

Naratriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Naratriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Naratriptan is used to treat migraine headaches.

Naratriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Naratriptan should not be used to treat common tension headaches or any headache that seems to be different from your ususal migraine headaches. Use this medication only if your condition has been confirmed by a doctor as migraine headaches.

Naratriptan may also be used for other purposes not listed in this medication guide.

Precautions

Instructions

Side Effects

Interactions

Precautions

You should not take this medication if you are allergic to naratriptan, or if you have a history of heart disease, angina (chest pain), blood circulation problems, ischemic bowel disease, severe liver or kidney disease, uncontrolled high blood pressure, or history of a heart attack or stroke.

You should not use this medication if you are allergic to naratriptan, or if you have:

• a history of heart disease, angina (chest pain), blood circulation problems, heart attack, or stroke, including "mini-stroke";
• ischemic bowel disease;
• severe liver disease;
• severe kidney disease;
• severe or uncontrolled high blood pressure; or
• a headache that is not like other headaches you have had.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking naratriptan, tell your doctor if you have:

• liver disease;
• kidney disease;
• heart disease, high blood pressure, a heart rhythm disorder; or
• coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before taking naratriptan, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Your name may need to be listed on a naratriptan pregnancy registry when you start using this medication.

Naratriptan can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone younger than 18 or older than 65.

Do not take naratriptan within 24 hours before or after using another migraine headache medicine, including:

• almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex, Treximet), or zolmitriptan (Zomig); or
• ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), or methysergide (Sansert).

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose could cause high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizure).

Since naratriptan is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using naratriptan.

After taking a naratriptan tablet, you must wait four (4) hours before taking a second tablet. Do not take more than two (2) naratriptan tablets in 24 hours.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using naratriptan and call your doctor at once if you have any of these serious side effects:

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• sudden and severe stomach pain and bloody diarrhea;
• numbness or tingling and a pale or blue-colored appearance in your fingers or toes; or
• (if you are also taking an antidepressant) - agitation, high fever, sweating, fast or pounding heartbeats, nausea, vomiting, diarrhea, loss of balance or coordination, overactive reflexes, hallucinations, fainting.

Less serious side effects may include:

• dry mouth, mild nausea;
• feeling of pain or tightness in your jaw, neck, or throat;
• pressure or heavy feeling in any part of your body;
• dizziness, drowsiness, tired feeling; or
• warmth, redness, or mild tingling under your skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Before taking naratriptan, tell your doctor if you are using any of the following drugs:

• an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).

This list is not complete and there may be other drugs that can interact with naratriptan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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