Home > Community Treatment Reports and Side Effects > Trimethobenzamide

What is the most important information I should know about trimethobenzamide?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a trimethobenzamide overdose may include drowsiness, uncontrollable movements, muscle spasms, blurred vision, seizures or convulsions, difficulty breathing, and death.

Trimethobenzamide may increase the side effects of other drugs that make you sleepy (such as alcohol, cold medicine, pain medication, muscle relaxants, and medicine for seizures, depression or anxiety). Before using trimethobenzamide, tell your doctor if you are using any of these medicines.

Trimethobenzamide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while you are using trimethobenzamide. Alcohol may increase drowsiness and dizziness.

Warning

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Back to Treatment Report

What is trimethobenzamide?

Trimethobenzamide affects the areas of the brain that stimulate nausea and vomiting.

Trimethobenzamide is used to treat nausea and vomiting.

Trimethobenzamide may also be used for purposes other than those listed in this medication guide.

Precautions

Before taking this medication, tell your doctor if you have:

  • kidney or liver disease;
  • an enlarged prostate;
  • difficulty urinating or other bladder problems;
  • glaucoma;
  • asthma; or
  • heart disease or a heart rhythm disorder.

If you have any of these conditions, you may not be able to use trimethobenzamide, or you may need a dosage adjustment or special tests during treatment.

It is not known whether trimethobenzamide will be harmful to an unborn baby. Do not take trimethobenzamide without telling your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether trimethobenzamide passes into breast milk. Do not take trimethobenzamide without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child, especially if the child has a fever or has recently had chicken pox.

Trimethobenzamide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while you are using trimethobenzamide. Alcohol may increase drowsiness and dizziness.

Back to top

Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a trimethobenzamide overdose may include drowsiness, uncontrollable movements, muscle spasms, blurred vision, seizures or convulsions, difficulty breathing, and death.

This medicine is often used only when needed to control nausea or vomiting, so you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

Back to top

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction:hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • jaundice (yellowing of the skin or eyes);
  • seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • tremor (uncontrolled shaking); or
  • muscle cramps, severe muscle spasms.

Continue using trimethobenzamide and talk with your doctor if you have any of these less serious side effects:

  • drowsiness or dizziness;
  • headache;
  • feeling depressed or disoriented; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

Back to top

Interactions

Trimethobenzamide may increase the side effects of other drugs that make you sleepy (such as cold medicine, pain medication, muscle relaxants, and medicine for seizures, depression or anxiety). Before using trimethobenzamide, tell your doctor if you are using any of these medicines.

There may be other drugs that can affect trimethobenzamide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Back to top

Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04