You should not take this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic and others), valsartan (Diovan), or sulfa drugs, or if you are unable to urinate.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take this medication:
- kidney disease;
- liver disease;
- congestive heart failure;
- asthma or allergies;
- low or high levels of magnesium or potassium in your blood;
- lupus; or
FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use this medication without telling your doctor if you are pregnant. Amlodipine, hydrochlorothiazide, and valsartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.
Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of amlodipine, hydrochlorothiazide, and valsartan.
Do not use potassium supplements or salt substitutes while you are taking amlodipine, hydrochlorothiazide, and valsartan, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include fast or slow heartbeat, confusion, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; feeling light-headed, and fainting.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- feeling like you might pass out;
- swelling, rapid weight gain;
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- slow, fast, or pounding heartbeats;
- urinating less than usual, or not at all;
- easy bruising or bleeding, unusual weakness;
- numbness, burning, pain, or tingly feeling; or
- jaundice (yellowing of the skin or eyes); or
- dry mouth, increased thirst, drowsiness, restless feeling, confusion, increased urination, fast heart rate, fainting, or seizure (convulsions).
Less serious side effects may include:
- headache, tired feeling;
- nausea, upset stomach;
- muscle spasms, back pain; or
- stuffy nose, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially:
- any other blood pressure medications;
- steroids (prednisone and others);
- carbamazepine (Carbatrol, Tegretol);
- lithium (Eskalith, Lithobid);
- cholestyramine (Prevalite, Questran) or colestipol (Colestid);
- insulin or diabetes medications you take by mouth;
- a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
- any other diuretics (water pills);
- aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others;
- a muscle relaxer such as baclofen (Lioresal), carisoprodol (Soma), cyclobenzaprine (Flexeril), dantrolene (Dantrium), metaxalone (Skelaxin), or methocarbamol (Robaxin), orphenadrine (Norflex), or tizanidine (Zanaflex);
- a narcotic medication such as hydrocodone (Lortab, Vicodin), meperidine (Demerol), methadone (Methadose), morphine (Kadian, MS Contin), oxycodone (OxyContin), and others.
This list is not complete and there may be other drugs that can interact with amlodipine, hydrochlorothiazide, and valsartan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
amlodipine/hydrochlorothiazide/valsartan and Exforge HCT
Available Strengths & Dosages
|oral||tablet||5 mg-12.5 mg-160 mg|
|oral||tablet||10 mg-12.5 mg-160 mg|
|oral||tablet||5 mg-25 mg-160 mg|
|oral||tablet||10 mg-25 mg-160 mg|
|oral||tablet||10 mg-25 mg-320 mg|
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Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04