I started at 100mg. After being so grouchy & moody for months, it was like a "legal high" without the fuzzy head and all the side effects. I had not been that happy and content in years! I loved it. After a couple of months I went up to 150mg. It seemed like my body was getting used to it. The only side effect I had was staying tired all the time. I got to where I couldn't even do my daily activities because I was soo tired and had to nap everyday. Taking it at night helped some, but I was still too tired. I was scared if I switched to another drug I wouldn't do good or go back to how I felt before but a month later and so far so good!