Evaluations from Patients who take Lacosamide

**Purpose:** Epilepsy *(Started Nov 13, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Mar 16, 2010	200 mg/20 mL Daily	Major	Mild	Always	Not at all

Date: Mar 16, 2010
Advice & Tips: I was taking 3000 mg of Keppra per day when I began taking Vimpat and had to reduce the dosage 500 mg every 2 weeks. I feel like a new person. I was having 3-4 seizures per week; now I am only having 2 maybe 3 a month- I haven't driven since my first seizure in 2006 (I have absence seizures ) due to the number of seizures per day, but that is a small price to pay for actually having a life with so few seizures now. I still take 500 mg topamax also to help with seizure and migraine control but to not walk around in a "drug induced fog" is a blessing!

**Purpose:** Epilepsy *(Started Apr 22, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Nov 28, 2009	200 mg/20 mL Daily	Moderate	Moderate	Never	Very

Date: Nov 28, 2009
Advice & Tips: I changed from 100mg in the morning to 50mg in the morning the 50mg in the afternoon (still taking 100mg at night). I told my Dr & he said if it works then keep doing so.

**Purpose:** Seizures (complex partial) *(Started Apr 13, 2011)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
May 25, 2011	350 mg Daily	Major	Severe	Always	Very
Apr 28, 2011	350 mg Daily	Moderate	Severe	Always	Somewhat
Aug 02, 2010		Slight	Mild	Always	A little
May 10, 2010		Major	Mild	Always	Not at all

Side effects:: Excessive daytime sleepiness (somnolence), Glaucoma (Both eyes)

Date: May 25, 2011
Advice & Tips: So far, along with my 3000 mg of Depakote daily and 750 mg daily of Primadone I have found myself literally falling asleep at my desk at work.
Cost: < $25 monthly

Date: Apr 28, 2011
Advice & Tips: The doctor has been increasing the dose he said with the intent to get me off Primidon. In doing that I am taking samples that change periodically and he has given samples. I don't know what the cost will be.
Cost: $25-49 monthly

Date: Aug 02, 2010
Advice & Tips: The doctor is considering discontinuing Primidone if this works because he says it would decrease falling asleep all the time. If that works it will be a major benifit. I take it with breakfast and dinner. I think it has made me a little more drowsy adding it to the Depekote and Primidonel.
Cost: $25-49 monthly

Date: May 10, 2010
Advice & Tips: So far this has given me the best benifits with the least side effect of a sizure medication in the last several years. I take the medication, one tablet with breakfast and one with dinner.
Cost: $25-49 monthly

**Purpose:** Epilepsy *(Started Nov 28, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Jul 08, 2010	50 mg Daily	?Can't tell	Severe	Always	Not at all
Feb 15, 2010	100 mg Daily	?Can't tell	Moderate	Always	Not at all

Date: Jul 08, 2010
Advice & Tips: This is a controlled substance and many places need at least a week notice in refilling this. To get a new prescription from dr. to pharmacy was a pain in the but too. It had to be mailed and not faxed which took longer & this is a newer medication &not many places in our area have heard of this medication and have had to look it up to see what it is.

Date: Feb 15, 2010
Advice & Tips: This is a very new medication just put out. My doctor I just got had to look it up because she had never heard of it before and neither did the hospital she works for and the one I went to in December. I have had alot of side effects on this in which my old neurologist would not take me off of previous meds. due to side effects and he would do the same to this medication and this was causing more severe reactions. Currently i am trying to get off of this medication to a more safer one.

**Purpose:** Seizures (complex partial) *(Started May 10, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
May 05, 2010	400 mg Daily	Moderate	Mild	Always	Not at all

**Purpose:** Seizures (complex partial) *(Started Nov 01, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Apr 15, 2010	Daily	?Can't tell	Moderate	Always	Very
Mar 03, 2010	Daily	Major	Mild	Always	Somewhat

Side effects:: Loss of bladder control, Loss of bowel control, Muscle jerks, Excessive daytime sleepiness (somnolence)

**Purpose:** Epilepsy *(Started Jul 05, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Jul 07, 2011	400 mg Daily	Slight	None	Always	Not at all

**Purpose:** Epilepsy *(Started Jan 01, 2010)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Jan 01, 2011	2 x 200 mg/20 mL Daily	Moderate	Mild	Always	Not at all

**Purpose:** Seizures (complex partial) *(Started Jan 21, 2010)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Sep 22, 2010	400 mg Daily	None	Mild	Always	A little

Date: Sep 22, 2010
Advice & Tips: I have increased taking Vimpat and there is no reduction of seizures.

**Purpose:** Epilepsy *(Started Jun 02, 2009)*
Date	Dosage	Perceived effectiveness	Side Effects	Adherence	Burden
Mar 22, 2010	200 mg Daily	Major	Mild	Always	Not at all