Provigil isn't for everyone... My fatigue is so major, that I must take it. I often alternate taking it one day, then skipping the next. I find that it works better for me taking it this way. Don't take it past noon, or risk not being able to sleep. Exorbitant cost, even with insurance. Some days, I feel like I am going to race out of my skin, and get some anxiety after taking it. But, it sure beats the fatigue I experience when NOT taking it.