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What is Cyclosporine?

Cyclosporin is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It has been studied in transplants of skin, heart, kidney, lung, pancreas, bone marrow and small intestine.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Prevent organ rejection 147 13 Efficacy_major Efficacy_moderate Efficacy_none
Transplant rejection prevention 86 24 Efficacy_major Efficacy_moderate Efficacy_none
Kidney Transplant 5 0
Kidney Transplant 4 1 Efficacy_major
Other 3 0
Psoriasis 3 1 Efficacy_major

See all 223 patients currently taking Cyclosporine

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Reported Side Effects

Side effects as an overall problem

Severe
 4
Moderate
 26
Mild
 7
None
 5

Commonly reported side effects, conditions, and hospitalizations associated with Cyclosporine

Hair growth 7
Elevated blood pressure 3
Weight gain 2
Nausea 2
Facial hair excessive 2
Hair growth increased 2
See all 62 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Cyclosporine. See all 38 dosages ►

  25 mg daily 50 mg daily 75 mg daily 100 mg daily 125 mg daily 150 mg daily 175 mg daily 200 mg daily 250 mg daily 300 mg daily
  14 Number of Patients: 14 14 Number of Patients: 14 9 Number of Patients: 9 29 Number of Patients: 29 9 Number of Patients: 9 29 Number of Patients: 29 8 Number of Patients: 8 60 Number of Patients: 60 17 Number of Patients: 17 13 Number of Patients: 13  

Reported Stop Reasons

Why Patients Stopped Taking Cyclosporine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 35   Doctor's advice: 56%
Side effects too severe 18   Side effects too severe: 29%
Did not seem to work 11   Did not seem to work: 17%
Other 9   Other: 14%
Course of treatment ended 5   Course of treatment ended: 8%
Personal research 3   Personal research: 5%
Expense 1   Expense: 2%
Not indicated 1   Not indicated: 2%

See all 60 patients who’ve stopped taking Cyclosporine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Cyclosporine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Cyclosporine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Cyclosporine

Always
 36 86%
Usually
 6 14%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Cyclosporine

Very
 2 5%
Somewhat
 3 7%
A little
 13 31%
Not at all
 24 57%

Cost

Paid out of pocket

Cost of Cyclosporine

$200+
 5 22%
$100-199
 2 9%
$50-99
 4 17%
$25-49
 2 9%
< $25
 10 43%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 12, 2012.