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Home > Community Treatment Reports and Side Effects > Tacrolimus Treatment Report
What is Tacrolimus?

Tacrolimus (FK506) is an immunosuppressant agent. Taken orally or by injection it is used to prevent organ rejection in heart, kidney, or liver transplant recipients. Used as a topical skin product it is used for moderate-to-severe atopic dermatitis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Prevent organ rejection 499 26 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Transplant rejection prevention 359 80 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Transplant rejection 24 5 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Kidney Transplant 21 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Kidney Transplant 20 8 Efficacy_major Efficacy_slight
Liver transplant 15 2 Efficacy_major Efficacy_cant_tell

See all 990 patients currently taking Tacrolimus

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Reported Side Effects

Side effects as an overall problem

Severe
 11
Moderate
 31
Mild
 46
None
 37

Commonly reported side effects, conditions, and hospitalizations associated with Tacrolimus

Tremor in hands 23
Hair loss (alopecia) 18
Hair thinning 10
Shakiness 8
Fatigue 7
Essential Tremor 6
See all 110 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Tacrolimus. See all 83 dosages ►

  0.5 mg daily 1 mg daily 2 mg daily 3 mg daily 4 mg daily 5 mg daily 6 mg daily 7 mg daily 8 mg daily 10 mg daily
  43 Number of Patients: 43 74 Number of Patients: 74 166 Number of Patients: 166 122 Number of Patients: 122 184 Number of Patients: 184 83 Number of Patients: 83 102 Number of Patients: 102 23 Number of Patients: 23 61 Number of Patients: 61 44 Number of Patients: 44  

Reported Stop Reasons

Why Patients Stopped Taking Tacrolimus (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 15   Side effects too severe: 43%
Doctor's advice 12   Doctor's advice: 34%
Other 6   Other: 17%
Did not seem to work 5   Did not seem to work: 14%
Course of treatment ended 4   Course of treatment ended: 11%
Change in health plan coverage 3   Change in health plan coverage: 9%
Expense 2   Expense: 6%
Not indicated 1   Not indicated: 3%

See all 34 patients who’ve stopped taking Tacrolimus

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Tacrolimus

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Tacrolimus

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Tacrolimus

Always
 118 94%
Usually
 5 4%
Sometimes
 0 0%
Never
 2 2%

Burden

Difficulty being on treatment

Burden of Tacrolimus

Very
 4 3%
Somewhat
 3 2%
A little
 14 11%
Not at all
 104 83%

Cost

Paid out of pocket

Cost of Tacrolimus

$200+
 6 7%
$100-199
 7 8%
$50-99
 8 9%
$25-49
 7 8%
< $25
 57 66%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.