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What is Tizanidine HCl?

Tizanidine hydrochloride is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Stiffness/Spasticity 559 104 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle spasms 252 66 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 117 18 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle pain 83 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Pain 70 19 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle spasms in neck and shoulders 56 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 1243 patients currently taking Tizanidine HCl

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Reported Side Effects

Side effects as an overall problem

Severe
29
Moderate
66
Mild
77
None
87

Commonly reported side effects, conditions, and hospitalizations associated with Tizanidine HCl

Sleepiness 45
Dry mouth (xerostomia) 36
Dry eyes 19
Fatigue 18
Drowsiness 16
Muscle fatigue 9
See all 68 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Tizanidine HCl. See all 52 dosages

  2mg as needed daily 4mg as needed 2 mg daily 4 mg daily 6 mg daily 8 mg daily 12 mg daily 16 mg daily 24 mg daily
  33 Number of Patients: 33 34 Number of Patients: 34 87 Number of Patients: 87 120 Number of Patients: 120 319 Number of Patients: 319 80 Number of Patients: 80 195 Number of Patients: 195 135 Number of Patients: 135 75 Number of Patients: 75 37 Number of Patients: 37  

Reported Stop Reasons

Why Patients Stopped Taking Tizanidine HCl (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 92   Did not seem to work: 40%
Side effects too severe 55   Side effects too severe: 24%
Other 51   Other: 22%
Doctor's advice 48   Doctor's advice: 21%
Personal research 12   Personal research: 5%
Course of treatment ended 11   Course of treatment ended: 5%
Expense 9   Expense: 4%
Change in health plan coverage 3   Change in health plan coverage: 1%
Not indicated 1   Not indicated: 0%

See all 228 patients who’ve stopped taking Tizanidine HCl

Currently Taking Tizanidine HCl

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Tizanidine HCl

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Tizanidine HCl

Always
167 64%
Usually
56 22%
Sometimes
27 10%
Never
9 3%

Burden

Difficulty being on treatment

Burden of Tizanidine HCl

Very
14 5%
Somewhat
15 6%
A little
47 18%
Not at all
183 71%

Cost

Paid out of pocket

Cost of Tizanidine HCl

$200+
1 1%
$100-199
0 0%
$50-99
11 6%
$25-49
22 12%
< $25
154 82%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.