What is Lamotrigine?
Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.
Reported Side Effects
Side effects
as an overall problem
Commonly reported side effects, conditions, and hospitalizations associated with Lamotrigine
|
Dizziness
|
56 |
|
|
Headaches
|
51 |
|
|
Problems concentrating
|
44 |
|
|
Insomnia
|
36 |
|
|
Sleepiness
|
33 |
|
|
Tremor in hands
|
26 |
|
|
Weight gain
|
25 |
|
|
Memory problems
|
23 |
|
|
Nausea
|
21 |
|
|
Nightmares
|
18 |
|
|
Fatigue
|
16 |
|
|
Vivid dreams
|
15 |
|
|
Rash or skin problems
|
13 |
|
|
Blurry vision
|
12 |
|
|
Drowsiness
|
11 |
|
|
Dry mouth (xerostomia)
|
11 |
|
|
Excessive daytime sleepiness (somnolence)
|
10 |
|
|
Word fishing
|
9 |
|
|
Anxious mood
|
9 |
|
|
Rashes (redness, swelling)
|
8 |
|
|
Tiredness
|
8 |
|
|
Hair loss (alopecia)
|
7 |
|
|
Brain fog
|
7 |
|
|
Double vision (diplopia)
|
7 |
|
|
Forgetting Words
|
6 |
|
|
Balance problems
|
6 |
|
|
Itching (pruritus)
|
6 |
|
|
Depressed mood
|
6 |
|
|
Heart palpitations
|
5 |
|
|
Acne
|
5 |
|
|
Loss of short term memory
|
5 |
|
|
Sex drive (libido) decreased
|
4 |
|
|
Diarrhea
|
4 |
|
|
Suicidal thoughts or urges
|
4 |
|
|
Rash on face
|
4 |
|
|
Menstrual cramps
|
4 |
|
|
Constipation
|
4 |
|
|
Cognitive impairment
|
4 |
|
|
Emotional numbness or flatness
|
4 |
|
|
Hyperactivity
|
3 |
|
|
Dry skin
|
3 |
|
|
Stupidity or "stupids" effect
|
3 |
|
|
Generalized itching
|
3 |
|
|
Short term memory problems
|
3 |
|
|
Mood swings
|
3 |
|
|
Memory lapses (brain blinks)
|
3 |
|
|
Ringing in ears (tinnitus)
|
3 |
|
|
Dry eyes
|
3 |
|
|
Difficulty sleeping through night
|
3 |
|
|
Nausea and vomiting
|
3 |
|
|
Night sweats
|
3 |
|
|
Hospitalization
|
3 |
|
|
Muscle pain
|
3 |
|
|
Anger
|
2 |
|
|
Slurred speech
|
2 |
|
|
Skin rash
|
2 |
|
|
Need to eat to help with Nausea
|
2 |
|
|
Joint pain
|
2 |
|
|
Lethargy
|
2 |
|
|
Stomach upset
|
2 |
|
|
Makes me emotional or short fused
|
2 |
|
|
slowed reaction time
|
2 |
|
|
Eye pain
|
2 |
|
|
Mood changes
|
2 |
|
|
Allergic reaction
|
2 |
|
|
Problems with focusing eyes
|
2 |
|
|
Increased fatigue
|
2 |
|
|
Feet Tingling
|
2 |
|
|
Muscle spasms
|
2 |
|
|
Clumsiness
|
2 |
|
|
Hands Tingling
|
2 |
|
|
Memory and cognition problems
|
2 |
|
|
Spaced out
|
2 |
|
|
Forgetfulness
|
2 |
|
|
Sore throat (Pharyngitis)
|
2 |
|
|
Spinning dizziness (vertigo)
|
2 |
|
|
Nerve pain (neuralgia)
|
2 |
|
|
Stuttering
|
2 |
|
|
Irritability
|
2 |
|
|
Word finding difficulty
|
2 |
|
|
Mouth sores (ulcers)
|
2 |
|
|
Unintentional weight loss
|
2 |
|
|
Itchy skin
|
2 |
|
|
Dry tongue
|
2 |
|
|
Dizziness upon standing (ie too quickly)
|
2 |
|
|
Aggression
|
2 |
|
|
Falls
|
2 |
|
|
Headaches all day
|
2 |
|
|
Daytime sleepiness
|
2 |
|
|
Morning sleepiness
|
2 |
|
|
Sedation
|
2 |
|
|
Jittery feeling
|
2 |
|
|
Suicidal ideation
|
2 |
|
|
Agitation
|
2 |
|
|
Lymphadenopathy
|
2 |
|
|
Stevens Johnson Syndrome
|
2 |
|
|
Hands shaking to relieve anxiety
|
1 |
|
|
Memory Loss
|
1 |
|
|
Low bone mineral density
|
1 |
|
|
Migraine headaches
|
1 |
|
|
Hair thinning
|
1 |
|
|
Blood pressure decreased
|
1 |
|
|
Can't recall words or enterrupted throught process
|
1 |
|
|
Unrefreshing or poor sleep
|
1 |
|
|
Mental confusion
|
1 |
|
|
Muscle aches
|
1 |
|
|
Inflammation
|
1 |
|
|
Swelling in hands
|
1 |
|
|
Pimples
|
1 |
|
|
hives/swelling of lips and tongue
|
1 |
|
|
Swelling in feet
|
1 |
|
|
Outburst of anger
|
1 |
|
|
Urine smell abnormal
|
1 |
|
|
Happy
|
1 |
|
|
Feeling out of it
|
1 |
|
|
Anxiety with driving
|
1 |
|
|
Hostility
|
1 |
|
|
Feeling sick
|
1 |
|
|
Mucus in throat
|
1 |
|
|
Scars
|
1 |
|
|
Mid-cycle spotting
|
1 |
|
|
Generalized muscle weakness
|
1 |
|
|
Nerve Sensitivity (Pins and needles all over, skin hurts against clothes)
|
1 |
|
|
Unsteadiness
|
1 |
|
|
It made me lethargic (before I started the provigil)
|
1 |
|
|
Nosebleed(s)
|
1 |
|
|
Not dreaming
|
1 |
|
|
Headaches in morning
|
1 |
|
|
Itchy ears
|
1 |
|
|
Episodic dizziness
|
1 |
|
|
Suicidal thoughts (free floating)
|
1 |
|
|
Impulsive rage
|
1 |
|
|
Bumping into things (clumsiness)
|
1 |
|
|
Sinus infection with calcification
|
1 |
|
|
Swollen tongue
|
1 |
|
|
Absent minded
|
1 |
|
|
Status epilepticus
|
1 |
|
|
Mentally dull
|
1 |
|
|
Sex drive (libido) increased
|
1 |
|
|
Mixing up words
|
1 |
|
|
Rash/feet/face
|
1 |
|
|
Tremor in left hand
|
1 |
|
|
Seizures (complex partial)
|
1 |
|
|
Anxiety attacks
|
1 |
|
|
eye sight is getting worse and not because of age.
|
1 |
|
|
Excessive sleeping (hypersomnia)
|
1 |
|
|
Loss of balance
|
1 |
|
|
Increased or worsened depression
|
1 |
|
|
Hormonal imbalance
|
1 |
|
|
Anorexia (appetite loss)
|
1 |
|
|
Vertigo
|
1 |
|
|
Increased anxiety
|
1 |
|
|
Drowsy in a.m.
|
1 |
|
|
Robot/Zombie feelings
|
1 |
|
|
Low grade fever
|
1 |
|
|
Slowed thinking and comprehension
|
1 |
|
|
Chest tightness
|
1 |
|
|
Increased seizures
|
1 |
|
|
Lip smacking
|
1 |
|
|
Decreased depression
|
1 |
|
|
Aggravation
|
1 |
|
|
Better sleep
|
1 |
|
|
Uncontrollable Anger
|
1 |
|
|
Bad mood
|
1 |
|
|
I forgot I keep falling and bang my self up fairly bad, like cuts and brusies especially on my legs and arms I feel humiliated!
|
1 |
|
|
flat
|
1 |
|
|
N/A
|
1 |
|
|
Feel like a zombie
|
1 |
|
|
Panic, manic, over-stimulated
|
1 |
|
|
Daytime tiredness
|
1 |
|
|
Dizziness with disorientation
|
1 |
|
|
Rash on legs
|
1 |
|
|
Sleep Difficulties/Unpleasant Feeling on a tip of my tongue
|
1 |
|
|
Roughness on my face skin -not rash
|
1 |
|
|
Strange sensation on tip of my tongue
|
1 |
|
|
Breakthrough intermenstrual bleeding
|
1 |
|
|
Solemn affect with lower sex drive
|
1 |
|
|
Close left eye for good vision
|
1 |
|
|
Occasional balance problems on standing or walking too fast
|
1 |
|
|
none now, but i have a maniac episode once a year
|
1 |
|
|
Hair curling
|
1 |
|
|
tired, nonchalant attitude.
|
1 |
|
|
Head pain, migraines
|
1 |
|
|
Alternating constipation and diarrhea
|
1 |
|
|
Heavy Periods
|
1 |
|
|
Occasional constipation
|
1 |
|
|
Buzzing sensation in the brain area
|
1 |
|
|
Feeling better
|
1 |
|
|
Deja vu
|
1 |
|
|
Headache at start and with increased dose
|
1 |
|
|
Swelling in ankles
|
1 |
|
|
Sharp left side chest pain
|
1 |
|
|
Black stools
|
1 |
|
|
Feeling strange
|
1 |
|
|
Sinus tachycardia
|
1 |
|
|
Anticonvulsant at toxic levels
|
1 |
|
|
Loss of coordination
|
1 |
|
|
Pain in eyeballs
|
1 |
|
|
Tired eyes
|
1 |
|
|
Tongue sores
|
1 |
|
|
This medication really worked very well and balanced my mood all day long!
|
1 |
|
|
Lethargic in the evening
|
1 |
|
|
Sleeping better
|
1 |
|
|
Head rushes when taken at night
|
1 |
|
|
Possibly causing a petechial rash on arms and legs, body aches
|
1 |
|
|
Erythema migrans (bull's eye rash)
|
1 |
|
|
RA (Rheumatoid Arthritis)
|
1 |
|
|
Psychosis Disorder
|
1 |
|
|
Essential Tremor
|
1 |
|
|
Chemical/Venom Allergy
|
1 |
|
|
Tension Headache
|
1 |
|
|
Mild Depression
|
1 |
|
|
Acne
|
1 |
|
|
I had experienceds a brief period of nervousness, as the dosage was increased.
|
1 |
|
|
Stiffness/Spasticity
|
1 |
|
|
Pain
|
1 |
|
|
Heavy sensation
|
1 |
|
|
Tremor
|
1 |
|
|
Generalized muscle aches
|
1 |
|
|
Heartburn
|
1 |
|
|
Low blood pressure
|
1 |
|
|
Excessive yawning
|
1 |
|
|
Cramps in calf muscles
|
1 |
|
|
Sexual dysfunction
|
1 |
|
|
Shortness of breath (dyspnea)
|
1 |
|
|
Acid reflux
|
1 |
|
|
Walking problems
|
1 |
|
|
Weight loss
|
1 |
|
|
Cognitive Confusion
|
1 |
|
|
Abdominal bloating
|
1 |
|
|
Burning sensation in skin
|
1 |
|
|
Nystagmus
|
1 |
|
|
Cough
|
1 |
|
|
Imbalance when walking
|
1 |
|
|
Sweating
|
1 |
|
|
Muscle twitching (fasciculations)
|
1 |
|
|
Atrophy of right arm muscles
|
1 |
|
|
Irritable and grouchy
|
1 |
|
|
Decreased appetite
|
1 |
|
|
Swollen glands
|
1 |
|
|
Stomach pain
|
1 |
|
|
Speech problems
|
1 |
|
|
Vision Abnormalities (Halos/Floaters/Snow)
|
1 |
|
|
Vestibular balance problems
|
1 |
|
|
Seizures (grand mal or tonic-clonic)
|
1 |
|
|
Anxiety and frustration
|
1 |
|
|
Fever
|
1 |
|
|
Nasal congestion
|
1 |
|
|
Gait problems
|
1 |
|
|
Runny nose (rhinorrhea)
|
1 |
|
|
Suicidal
|
1 |
|
|
Pain in upper back
|
1 |
|
|
Self injury or harm
|
1 |
|
|
Sensitivity to loud sounds
|
1 |
|
|
Dissociation
|
1 |
|
|
Body weakness
|
1 |
|
|
Sweating excessive
|
1 |
|
|
Neurological fatigue
|
1 |
|
|
Mania
|
1 |
|
|
Sleeplessness
|
1 |
|
|
Visual disturbance
|
1 |
|
|
Racing thoughts
|
1 |
|
|
Skin sensitive to touch
|
1 |
|
|
None
|
1 |
|
|
Limbs Tingling
|
1 |
|
|
Sadness
|
1 |
|
|
Confusion
|
1 |
|
|
Lightheadedness
|
1 |
|
|
Aphasia
|
1 |
|
|
Facial swelling
|
1 |
|
|
Dry throat
|
1 |
|
|
Easily angry
|
1 |
|
|
Waking up feeling like you never slept
|
1 |
|
|
Brain zaps
|
1 |
|
|
Loss of reading comprehension (english)
|
1 |
|
|
Poor working memory
|
1 |
|
|
Paresthesia
|
1 |
|
|
Pain in rib
|
1 |
|
|
Grogginess
|
1 |
|
|
Lumps and bumps
|
1 |
|
|
Shakiness
|
1 |
|
|
Somnolence
|
1 |
|
|
Dizziness and feeling faint
|
1 |
|
|
Agitation with restlessness
|
1 |
|
|
Itchy rash
|
1 |
|
|
Ataxia (lack of coordination)
|
1 |
|
|
Poor Concentration
|
1 |
|
|
Thirst
|
1 |
|
|
Flu like symptoms
|
1 |
|
|
Loss of sex drive (libido)
|
1 |
|
|
Withdrawal effects
|
1 |
|
|
Sweating increased
|
1 |
|
|
Short temper
|
1 |
|
|
Muscle weakness in arms
|
1 |
|
|
Using or saying the wrong word
|
1 |
|
|
Muscle jerks
|
1 |
|
|
Sleep problems
|
1 |
|
|
Lack of concentration
|
1 |
|
|
Edema of extremities
|
1 |
|
|
see tiny sparkles
|
1 |
|
|
Slowed thinking
|
1 |
|
|
Loss of fine motor skills
|
1 |
|
|
Urinary problems
|
1 |
|
|
Dry hair
|
1 |
|
|
Allergies
|
1 |
|
|
Some brief fatigue
|
1 |
|
|
Loss of appetite
|
1 |
|
|
Non hormonal hot flushes
|
1 |
|
|
Muscle twitching in arms
|
1 |
|
|
See all
309 reported side effects
▼
See top
6 reported side effects
▲
|
Currently Taking Lamotrigine
A bar graph
Stopped Taking Lamotrigine
A bar graph
Adherence
Taking treatment as prescribed
Adherence of Lamotrigine
Always |
568
|
82%
|
|
Usually |
92
|
13%
|
|
Sometimes |
19
|
3%
|
|
Never |
13
|
2%
|
|
Burden
Difficulty being on treatment
Burden of Lamotrigine
Very |
26
|
4%
|
|
Somewhat |
72
|
10%
|
|
A little |
129
|
19%
|
|
Not at all |
465
|
67%
|
|
Cost
Paid out of pocket
Cost of Lamotrigine
$200+ |
16
|
4%
|
|
$100-199 |
25
|
6%
|
|
$50-99 |
29
|
7%
|
|
$25-49 |
62
|
14%
|
|
< $25 |
302
|
69%
|
|
See more information,
including instructions, precautions, side effects, and interactions.
