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What is Diaphragm Pacing Implant?

The NeuRX RA/4 System is a system designed to help patient’s breathing by stimulation of their diaphragm muscles. The stimulator provides repetitive electrical stimulation to the implanted electrodes to cause the patient’s diaphragm to contract and help the patient to breathe.

Synapse Biomedical Inc.'s Diaphragm Pacing Implant site

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
ALS (Amyotrophic Lateral Sclerosis) 20 9 Efficacy_major Efficacy_moderate Efficacy_none Efficacy_cant_tell
Other 5 1 Efficacy_major
supporting to breathe 4 1 Efficacy_major
Shortness of breath (dyspnea) 1 0

See all 28 patients currently using Diaphragm Pacing Implant

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
1
Mild
3
None
7

Commonly reported side effects, conditions, and hospitalizations associated with Diaphragm Pacing Implant

difficulty speaking when machine is on 4
Hospitalization 4
Breathing difficulty 1
None 1

Reported Schedules

Frequently reported dosages based on patients currently using Diaphragm Pacing Implant. See all 21 dosages

  daily 11 hr daily 12 hr daily 15 hr daily 16 hr daily 18 hr daily 22 hr daily 24 hr daily 90 min daily 140 min daily
  5 Number of Patients: 5 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 3 Number of Patients: 3 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Using (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 1   Did not seem to work: 50%
Doctor's advice 1   Doctor's advice: 50%

See all 2 patients who’ve stopped using Diaphragm Pacing Implant

How Long Current Patients Have Been Using Diaphragm Pacing Implant

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

How Long Patients Used Before Stopping

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Diaphragm Pacing Implant

Always
5 45%
Usually
5 45%
Sometimes
0 0%
Never
1 9%

Burden

Difficulty being on treatment

Burden of Diaphragm Pacing Implant

Very
0 0%
Somewhat
2 18%
A little
3 27%
Not at all
6 55%

Cost

Paid out of pocket

Cost of Diaphragm Pacing Implant

$200+
3 60%
$100-199
0 0%
$50-99
0 0%
$25-49
0 0%
< $25
2 40%

Report created on May 28, 2012.