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What is Diphenoxylate and Atropine?

Diphenoxylate and atropine is used to control diarrhea. Diphenoxylate is an opioid agonist used for the treatment of diarrhea that acts by slowing intestinal contractions. Because opiates can be habit forming, atropine is added, which can make the user feel nausea or weak if too much is taken.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Diarrhea 17 5 Efficacy_major Efficacy_moderate Efficacy_slight
Bowel irritability 12 2 Efficacy_major Efficacy_moderate
Diarrhea chronic 11 1 Efficacy_major
IBS (Irritable Bowel Syndrome) 5 2 Efficacy_major Efficacy_moderate
Support digestive health 3 0
Other 3 1 Efficacy_moderate

See all 45 patients currently taking Diphenoxylate and Atropine

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
0
Mild
8
None
4

Commonly reported side effects, conditions, and hospitalizations associated with Diphenoxylate and Atropine

Constipation 1
Dizziness 1
Dry mouth (xerostomia) 1
Headaches 1
Dry throat 1
Thirst 1
See all 7 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Diphenoxylate and Atropine. See all 22 dosages

  0.025mg-2.5mg as needed 2 0.025mg-2.5mg as needed 2.5mg as needed 2 mg daily 0.025 mg-2.5 mg daily 5 mg daily 2 x 0.025 mg-2.5 mg daily 4 x 0.025 mg-2.5 mg daily 15 mg daily 6 x 0.025 mg-2.5 mg daily
  11 Number of Patients: 11 2 Number of Patients: 2 6 Number of Patients: 6 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 3 Number of Patients: 3 5 Number of Patients: 5 2 Number of Patients: 2 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Diphenoxylate and Atropine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 4   Other: 44%
Course of treatment ended 3   Course of treatment ended: 33%
Did not seem to work 1   Did not seem to work: 11%
Personal research 1   Personal research: 11%
Doctor's advice 1   Doctor's advice: 11%
Side effects too severe 1   Side effects too severe: 11%

See all 8 patients who’ve stopped taking Diphenoxylate and Atropine

Currently Taking Diphenoxylate and Atropine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Diphenoxylate and Atropine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Diphenoxylate and Atropine

Always
9 75%
Usually
2 17%
Sometimes
1 8%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Diphenoxylate and Atropine

Very
0 0%
Somewhat
0 0%
A little
1 8%
Not at all
11 92%

Cost

Paid out of pocket

Cost of Diphenoxylate and Atropine

$200+
0 0%
$100-199
0 0%
$50-99
0 0%
$25-49
0 0%
< $25
4 100%

Report created on May 28, 2012.