Severe Migraines since age 18-36 years ago/ I have seen many neuros and had many MRI's. I was diagnosed in 03 at age of 46 with MS-vision was effected after my dear mother was hosp and then had to have a tracheotomy for pneumonia.I since tried and did not spend more than a few months on any of the CRAB meds. I tried Avonex, Betaseron Copaxone and Tysabrii-r 20 months. RECENTLY -carotid doppler showed block but, when the venogram could not find it. SInce had second carotid doppler and still shows block. I wait for a MRV for vessels in vein or chief vascular surgeon to try his hand w/me.