I am 37 years old and live in Northern California. I can remember symptoms that might have been an indicator as early as 18 years old but around the age of 23 I started noticing a tremor in my right hand that would come and go. By age 28 I was having stiffness in my arms and my tremors were becoming increasingly worse in my right hand where others were noticing it. It became hard to brush my teeth, my arm felt heavy, weak and unwilling to make the movement up and down. After a trip to UCSF at approximately age 28 it was confirmed, I had PD.