DX'd with Secondary Progressive Multiple Sclerosis in Feb., '97, after several years of tripping and stumbling. Began Betaseron in Dec. of '97. Used until Jan. of 2008, when bloodtest showed it had lost its "magic" (if there ever was any). Started taking Low Dose Naltrexone in March of this year, and had some fairly amazing results rather quickly. My aching pains, all over, began to disappear after the very first dose (3mg nightly, just before sleeping). By the end of the first week, ALL pains were gone, and the tingling-all-over began to diminish until, now, it is just in my hands.