I first was diagnosed with a stroke and I became very depressed . I did not want to go out much or interact with others . I started noticing that I was sleeping more and did not do anything social. I have now got many more symptoms like stiffness and difficulty walking and not sleeping as well at night. I started taking Synamit first and did well with it for about 6 months then I developed GI problems but still kept taking it but I lost alot of weight down to 140lbs so I was switched to Mirapax and took it for 2 years then I was not doing as well with walking or moving so Azelect was added