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Brand Names: Comtan, Comtess
Generic Name: Entacapone

What is Entacapone? Entacapone is COMT inhibitor drug which enhances the transport of l-dopa to the brain, improving the efficacy of l-dopa containing drugs such as Sinemet.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

102 patients in the community are taking or have taken Entacapone.

Reason # Patients Percentage of patients
Treat Parkinson's 79 77%
Stiffness/spasticity 6 5%
Other 6 5%
Support another treatment 2 1%
disease-related symptoms 1 <1%
Slowness 1 <1%

Dosages

Based on the patients currently taking Entacapone.

Top 10 (Show all)

All (Show Top 10)

  0 mg day 1 mg day 20 mg day 0 mg none 200 mg day 300 mg day 400 mg day 600 mg day 800 mg day 900 mg day 1000 mg day 1200 mg day
  8 Number of Patients: 8 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 13 Number of Patients: 13 4 Number of Patients: 4 8 Number of Patients: 8 20 Number of Patients: 20 22 Number of Patients: 22 1 Number of Patients: 1 8 Number of Patients: 8 2 Number of Patients: 2  

Duration

How long current patients have been taking Entacapone or how long patients were taking Entacapone before stopping.

Currently taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
7
9
14
6
24

Stopped taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
1
1
3
2
4
Why Patients Stopped Taking Entacapone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 8 62% Side effects too severe: 62%
Other 5 38% Other: 38%
Did not seem to work 3 23% Did not seem to work: 23%
Doctor's advice 1 8% Doctor's advice: 8%
Course of treatment ended 1 8% Course of treatment ended: 8%

Patient Reported Evaluations

Results from 4 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Moderate 50% 2
Slight 25% 1
Can't tell 25% 1

Treat Parkinson's

Side-effects (as an overall problem)

Severe 0% 0
Moderate 0% 0
Mild 25% 1
None 75% 3

Top reported side-effects include: Increased dyskenisia

Summary results are based on 4 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 4)

  • EfficacyCan't tell
  • Side-effectsNone
  • Treat Parkinson's

  • asb
    Mouth/throat: none
    Arms: mild
    Chest: none
    Legs: mild
    See profile
  • asb
  • by asb
    Sep 14, 2008
  • EfficacyModerate
  • Side-effectsNone
  • Treat Parkinson's
Advice/Tips
Almost immediate improvement against insomnia, but gradual backslide over 2 months. Follow up has been Sinemet CR

See all evaluation results for Entacapone



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