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Home > Community Treatment Reports > Entacapone Treatment Report
What is Entacapone?

Entacapone is an inhibitor of catechol-O-methyltransferase (COMT) and is indicated as an adjunct treatment for patients taking levodopa and carbidopa for Parkinson’s Disease who experience the signs and symptoms of end-of-dose “wearing-off”.

Side Effects

Side effects as an overall problem

Severe
4 15%
Moderate
5 19%
Mild
6 23%
None
11 42%

Most commonly reported side effects

Dyskinesia
5 36%
Digestive problems
5 36%
Constipation
4 29%
Nausea
2 14%
excessive perspiration
2 14%
on-off time
2 14%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Entacapone. See all 20 dosages

  200 mg all the time (24/7) 200 mg as needed 200mg as needed daily 1 mg daily 20 mg daily 100 mg daily 200 mg daily 250 mg daily 300 mg daily 400 mg daily 500 mg daily 600 mg daily 800 mg daily 900 mg daily 1000 mg daily 1200 mg daily 1400 mg daily 1600 mg daily 8200 mg daily
  2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 6 Number of Patients: 6 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 25 Number of Patients: 25 1 Number of Patients: 1 6 Number of Patients: 6 11 Number of Patients: 11 1 Number of Patients: 1 38 Number of Patients: 38 36 Number of Patients: 36 1 Number of Patients: 1 20 Number of Patients: 20 11 Number of Patients: 11 2 Number of Patients: 2 5 Number of Patients: 5 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Entacapone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe
12 36% Side effects too severe: 36%
Did not seem to work
8 24% Did not seem to work: 24%
Doctor's advice
8 24% Doctor's advice: 24%
Other
7 21% Other: 21%
Expense
3 9% Expense: 9%

See all 30 patients who’ve stopped taking Entacapone

Currently Taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Always
16 62%
Usually
10 38%
Sometimes
0 0%
Never
0 0%

Burden

Difficulty being on treatment

Very
1 4%
Somewhat
3 12%
A little
5 19%
Not at all
17 65%

Cost

Paid out of pocket

$200+
2 8%
$100-199
1 4%
$50-99
1 4%
$25-49
4 15%
< $25
10 38%

See more information, including instructions, precautions, side effects, and interactions.

Report created on March 22, 2010.