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Brand Names: Comtan, Comtess

What is Entacapone? Entacapone is a catechol-o-methyltransferase (COMT) inhibitor drug which enhances the transport of levodopa to the brain, improving the efficacy of levodopa containing drugs such as Sinemet.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

127 patients in the community are taking or have taken Entacapone.

Reason # Patients Percentage of patients
Treat Parkinson's 85 66%
Other 7 5%
Stiffness/spasticity 6 4%
Support another treatment 4 3%
disease-related symptoms 1 <1%
Mobility 1 <1%
Slowness 1 <1%

Dosages

Based on the patients currently taking Entacapone.

Top 10 (Show all)

All (Show Top 10)

  0 mg Daily 1 mg Daily 20 mg Daily 100 mg Daily 200 mg As needed 200 mg Daily 300 mg Daily 400 mg Daily 600 mg Daily 800 mg Daily 1000 mg Daily 1200 mg Daily 1400 mg Daily 1600 mg Daily
  8 Number of Patients: 8 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 17 Number of Patients: 17 4 Number of Patients: 4 11 Number of Patients: 11 27 Number of Patients: 27 23 Number of Patients: 23 10 Number of Patients: 10 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking Entacapone or how long patients were taking Entacapone before stopping.

Currently taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
4
11
8
12
10
22

Stopped taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
3
2
1
6
2
3
Why Patients Stopped Taking Entacapone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 8 44% Side effects too severe: 44%
Other 6 33% Other: 33%
Did not seem to work 5 28% Did not seem to work: 28%
Doctor's advice 4 22% Doctor's advice: 22%
Course of treatment ended 1 6% Course of treatment ended: 6%

Patient Reported Evaluations

Results from 8 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 40% 2
Moderate 40% 2
Slight 20% 1

Treat Parkinson's

Side-effects (as an overall problem)

Severe 13% 1
Moderate 0% 0
Mild 25% 2
None 63% 5

Top reported side-effects include: Increased dyskenisia, digestive problems

Summary results are based on 8 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (1 of 8)

  • asb
    Sex: M
    Mouth/throat: none
    Arms: mild
    Chest: none
    Legs: mild
    See profile
  • asb
  • by asb
    Sep 14, 2008
  • EfficacyModerate
  • Side-effectsNone
  • Treat Parkinson's
Advice/Tips
Almost immediate improvement against insomnia, but gradual backslide over 2 months. Follow up has been Sinemet CR

See all evaluation results for Entacapone



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