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What is Promethazine?

Promethazine is an antiemetic and antihistamine. It is used to relieve the symptoms of allergic reactions, nausea, motion sickness. It is also use as a sedative, as adjunctive therapy for postoperative pain, anesthetic and anaphylactic reactions.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Nausea 142 25 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Nausea and vomiting 52 15 Efficacy_major Efficacy_moderate
Migraine headaches 29 4 Efficacy_major Efficacy_moderate Efficacy_none
Other 23 3 Efficacy_major Efficacy_moderate
Nausea sometimes 12 3 Efficacy_major
migraine and nausea and vomiting 12 2 Efficacy_major

See all 301 patients currently taking Promethazine

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Reported Side Effects

Side effects as an overall problem

Severe
 3
Moderate
 13
Mild
 20
None
 28

Commonly reported side effects, conditions, and hospitalizations associated with Promethazine

Drowsiness 13
Excessive daytime sleepiness (somnolence) 2
Oversedation 2
Sedation 2
Disorientation 2
Groggy in morning 2
See all 19 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Promethazine. See all 36 dosages ►

  25mg as needed 50mg/mL as needed 50mg as needed 25mg/mL as needed 12.5mg as needed 12.5 mg daily 25 mg daily 50 mg daily 75 mg daily 100 mg daily
  126 Number of Patients: 126 6 Number of Patients: 6 7 Number of Patients: 7 37 Number of Patients: 37 16 Number of Patients: 16 6 Number of Patients: 6 33 Number of Patients: 33 22 Number of Patients: 22 9 Number of Patients: 9 12 Number of Patients: 12  

Reported Stop Reasons

Why Patients Stopped Taking Promethazine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 18   Course of treatment ended: 33%
Other 13   Other: 24%
Doctor's advice 13   Doctor's advice: 24%
Side effects too severe 9   Side effects too severe: 16%
Did not seem to work 6   Did not seem to work: 11%
Expense 1   Expense: 2%
Change in health plan coverage 1   Change in health plan coverage: 2%

See all 54 patients who’ve stopped taking Promethazine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Promethazine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Promethazine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Promethazine

Always
 40 63%
Usually
 14 22%
Sometimes
 9 14%
Never
 1 2%

Burden

Difficulty being on treatment

Burden of Promethazine

Very
 1 2%
Somewhat
 3 5%
A little
 9 14%
Not at all
 51 80%

Cost

Paid out of pocket

Cost of Promethazine

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 1 3%
< $25
 37 97%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.