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What is Domperidone?

Domperidone is an antidopaminergic drug used to suppress nausea or vomiting. It can be used in the treatment of gastrointestinal disorders, or may be administered as an antiemetic with drugs such as apomorphine to prevent feelings of sickness that can arise from such drugs.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Nausea 16 6 Efficacy_major Efficacy_moderate Efficacy_slight
Gastroparesis 9 4 Efficacy_moderate Efficacy_slight
Constipation 6 0
Gastroparesis 5 1 Efficacy_moderate
Other 4 2 Efficacy_major Efficacy_cant_tell
Nausea and vomiting 3 1 Efficacy_moderate

See all 54 patients currently taking Domperidone

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
0
Mild
4
None
15

Commonly reported side effects, conditions, and hospitalizations associated with Domperidone

Muscle cramps 1
Nausea sometimes 1
Abdominal cramps 1
Bowel (fecal) incontinence 1

Reported Dosages

Frequently reported dosages based on patients currently taking Domperidone. See all 14 dosages

  10mg as needed 3 mg daily 4 other daily 10 mg daily 15 mg daily 20 mg daily 30 mg daily 40 mg daily 60 mg daily 80 mg daily
  8 Number of Patients: 8 2 Number of Patients: 2 1 Number of Patients: 1 7 Number of Patients: 7 1 Number of Patients: 1 4 Number of Patients: 4 14 Number of Patients: 14 12 Number of Patients: 12 2 Number of Patients: 2 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Domperidone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 5   Did not seem to work: 36%
Other 4   Other: 29%
Doctor's advice 2   Doctor's advice: 14%
Side effects too severe 2   Side effects too severe: 14%
Course of treatment ended 1   Course of treatment ended: 7%
Not indicated 1   Not indicated: 7%

See all 14 patients who’ve stopped taking Domperidone

Currently Taking Domperidone

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Domperidone

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Domperidone

Always
13 62%
Usually
6 29%
Sometimes
1 5%
Never
1 5%

Burden

Difficulty being on treatment

Burden of Domperidone

Very
1 5%
Somewhat
1 5%
A little
5 24%
Not at all
14 67%

Cost

Paid out of pocket

Cost of Domperidone

$200+
0 0%
$100-199
0 0%
$50-99
2 14%
$25-49
2 14%
< $25
10 71%

Report created on February 10, 2012.