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What is Propoxyphene-Acetaminophen?

This is an opioid analgesic combination of propoxyphene and acetaminophen used for mild to moderate pain. In 2010 the FDA sought market withdrawal of propoxyphene and requested manufacturers voluntarily remove their products after new clinical data showed potential for serious heart risks.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Pain 242 72 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Fibromyalgia 26 9 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Other 24 5 Efficacy_major Efficacy_moderate Efficacy_slight
Breakthrough pain 18 8 Efficacy_major Efficacy_moderate Efficacy_slight
Pain in hips 13 5 Efficacy_moderate Efficacy_slight Efficacy_none
Back pain 11 4 Efficacy_moderate Efficacy_slight

See all 274 patients currently taking Propoxyphene-Acetaminophen

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
9
Mild
36
None
65

Reported Dosages

Frequently reported dosages based on patients currently taking Propoxyphene-Acetaminophen. See all 62 dosages

  napsylate650mg-100mg as needed napsylate325mg-50mg as needed napsylate500mg-100mg as needed 100mg as needed 2 napsylate650mg-100mg as needed napsylate 500 mg-100 mg daily napsylate 650 mg-100 mg daily 2 x napsylate 650 mg-100 mg daily 3 x napsylate 650 mg-100 mg daily 4 x napsylate 650 mg-100 mg daily
  87 Number of Patients: 87 5 Number of Patients: 5 7 Number of Patients: 7 18 Number of Patients: 18 9 Number of Patients: 9 5 Number of Patients: 5 27 Number of Patients: 27 17 Number of Patients: 17 9 Number of Patients: 9 15 Number of Patients: 15  

Reported Stop Reasons

Why Patients Stopped Taking Propoxyphene-Acetaminophen (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 51   Other: 36%
Did not seem to work 37   Did not seem to work: 26%
Doctor's advice 33   Doctor's advice: 23%
Course of treatment ended 22   Course of treatment ended: 15%
Side effects too severe 10   Side effects too severe: 7%
Personal research 4   Personal research: 3%
Change in health plan coverage 1   Change in health plan coverage: 1%
Not indicated 1   Not indicated: 1%

See all 139 patients who’ve stopped taking Propoxyphene-Acetaminophen

Currently Taking Propoxyphene-Acetaminophen

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0

Stopped Taking Propoxyphene-Acetaminophen

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Propoxyphene-Acetaminophen

Always
54 48%
Usually
35 31%
Sometimes
18 16%
Never
5 4%

Burden

Difficulty being on treatment

Burden of Propoxyphene-Acetaminophen

Very
4 4%
Somewhat
6 5%
A little
16 14%
Not at all
86 77%

Cost

Paid out of pocket

Cost of Propoxyphene-Acetaminophen

$200+
1 1%
$100-199
0 0%
$50-99
1 1%
$25-49
7 8%
< $25
79 90%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.