From "ALS TODAY" Magazine:
The oligodendrocyte, a new player in ALS?
by: Michelle Pflumm, Ph.D.
In people with ALS, the motor nerves deteriorate leading to muscle weakness and paralysis. Astrocytes and microglia, entrusted to support and protect these cells, turn traitor spewing out neurotoxic cytokines, contributing to disease progression.
ALS, however, is fueled by much more than a perfect storm of neurotoxic substances. Motor neurons face an energy crisis. And, scientists suspect, are without a plan B. Oligodendrocytes, which may help keep the power on in motor neurons, are also disappearing over the course of the disease.
Read more: http://blogs.als.net/post/2012/07/19/The-oligodendrocyte-a-new-player-in-ALS.aspx