Webinar on the TDP-43 Mouse Model (link to recording from earlier this week)

Webinar on The TDP-43 Mouse Model
Featuring: Robert Baloh, Ph.D. (Washington University - St. Louis)
Fernando G. Vieira, M.D.(ALS TDI)

Over the last couple of years, a growing body of work has suggested that a genetic mutation leads to the mislocalization of TDP-43 outside of the nucleus of cells. Some research has linked this mutant protein activity to both familial as well as sporadic ALS. Our Institute has partnered with Dr. Baloh to develop a model of TDP-43 that could be used as a tool to screen potential therapeutics similar to the way that we developed and use the standard model of ALS; the SOD1 mouse. This 90 minute webinar provides an inside look into what TDP-43 is, why it is important, how this collaboration came about, how the experiment was designed, and where the team is in determining the phenotype of this mouse.

Click to view this important and in-depth discussion on TDP-43 and ALS