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What is 5-Hydroxytryptophan (5-HTP)?

5-Hydroxytryptophan or 5-HTP is a naturally-occurring amino acid marketed in the United States and other countries as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Depressed mood 19 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Treat my mood condition(s) 18 8 Efficacy_moderate Efficacy_none Efficacy_cant_tell
Fibromyalgia 17 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Insomnia 11 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Other 11 2 Efficacy_major Efficacy_cant_tell
Sleep problems 10 4 Efficacy_moderate Efficacy_slight

See all 94 patients currently taking 5-Hydroxytryptophan (5-HTP)

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
3
Mild
7
None
42

Commonly reported side effects, conditions, and hospitalizations associated with 5-Hydroxytryptophan (5-HTP)

Volatile mood 3
Vivid dreams 2
Heart palpitations 2
Dreams 2
Fatigue 2
Sleep problems 1
See all 13 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking 5-Hydroxytryptophan (5-HTP). See all 15 dosages

  300 mg weekly 50 mg daily 60 mg daily 100 daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily 400 mg daily 650 mg daily
  1 Number of Patients: 1 20 Number of Patients: 20 1 Number of Patients: 1 1 Number of Patients: 1 30 Number of Patients: 30 5 Number of Patients: 5 24 Number of Patients: 24 9 Number of Patients: 9 2 Number of Patients: 2 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking 5-Hydroxytryptophan (5-HTP) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 24   Did not seem to work: 39%
Other 15   Other: 25%
Expense 8   Expense: 13%
Doctor's advice 7   Doctor's advice: 11%
Course of treatment ended 6   Course of treatment ended: 10%
Not indicated 4   Not indicated: 7%
Side effects too severe 4   Side effects too severe: 7%
Personal research 2   Personal research: 3%
Change in health plan coverage 1   Change in health plan coverage: 2%

See all 61 patients who’ve stopped taking 5-Hydroxytryptophan (5-HTP)

Currently Taking 5-Hydroxytryptophan (5-HTP)

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking 5-Hydroxytryptophan (5-HTP)

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of 5-Hydroxytryptophan (5-HTP)

Always
37 69%
Usually
11 20%
Sometimes
6 11%
Never
0 0%

Burden

Difficulty being on treatment

Burden of 5-Hydroxytryptophan (5-HTP)

Very
1 2%
Somewhat
5 9%
A little
9 17%
Not at all
39 72%

Cost

Paid out of pocket

Cost of 5-Hydroxytryptophan (5-HTP)

$200+
0 0%
$100-199
0 0%
$50-99
0 0%
$25-49
7 18%
< $25
33 83%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 12, 2012.