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Brand Names:
Sirdalud Retard, Zanaflex
What is Tizanidine?
Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.
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324 patients in the community are taking or have taken Tizanidine.
| Reason | # Patients | Percentage of patients |
|---|---|---|
| Stiffness/spasticity | 239 | 73% |
| Other | 27 | 8% |
| Pain | 16 | 4% |
| disease-related symptoms | 5 | 1% |
| Muscle spasms, neck and shoulders | 4 | 1% |
| Muscle Spasms, feet and toes | 3 | <1% |
| Slow my MS progress | 3 | <1% |
| General health | 2 | <1% |
| Depression | 2 | <1% |
| Muscle twitching (fasciculations) | 1 | <1% |
| Burning sensation, soles of feet | 1 | <1% |
| Muscle cramping, spasms | 1 | <1% |
| Spasms, calves | 1 | <1% |
| Night-time leg spasms | 1 | <1% |
| Fatigue | 1 | <1% |
| MS Hug, or girdle-band sensation, stomach/chest/thighs | 1 | <1% |
| Spasms | 1 | <1% |
| Sexual dysfunction | 1 | <1% |
| Calf, feet cramps and muscle spasms | 1 | <1% |
| Cramps, calf muscles | 1 | <1% |
| twitches and jerks | 1 | <1% |
| Don't know | 1 | <1% |
| Support another treatment | 1 | <1% |
How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.
Results from 18 patient evaluations. See the overall results and all individual evaluations.
| Major | 41% | 7 |
|---|---|---|
| Moderate | 24% | 4 |
| Slight | 24% | 4 |
| None | 12% | 2 |
Insomnia
| Severe | 11% | 2 |
|---|---|---|
| Moderate | 33% | 6 |
| Mild | 28% | 5 |
| None | 28% | 5 |
Top reported side-effects include: sleepy, Fatigue, makes me very sleepy
Summary results are based on 18 individual responses. For more information, see overall results for Adherence, Burden and Cost.