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What is Diphenhydramine?

Diphenhydramine is an antihistamine. It is used to relieve irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. It may also be used to prevent and treat motion sickness, or to control abnormal movements in early stage parkinsonian syndrome.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Insomnia 86 27 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Allergies 63 12 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Other 54 13 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Sleep problems 24 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Food allergy 21 0
Itching (pruritus) 10 4 Efficacy_major Efficacy_slight

See all 288 patients currently taking Diphenhydramine

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Reported Side Effects

Side effects as an overall problem

Severe
 7
Moderate
 13
Mild
 27
None
 36

Commonly reported side effects, conditions, and hospitalizations associated with Diphenhydramine

Drowsiness 12
Brain fog 9
Sleepiness 7
Groggy in morning 3
Restless feeling in legs 2
Excessive daytime sleepiness (somnolence) 2
See all 24 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Diphenhydramine. See all 44 dosages ►

  2 25mg as needed 2 50mg as needed daily 50mg as needed 25mg as needed 25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily
  24 Number of Patients: 24 4 Number of Patients: 4 9 Number of Patients: 9 24 Number of Patients: 24 49 Number of Patients: 49 46 Number of Patients: 46 67 Number of Patients: 67 12 Number of Patients: 12 13 Number of Patients: 13 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Diphenhydramine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 35   Other: 41%
Did not seem to work 16   Did not seem to work: 19%
Course of treatment ended 15   Course of treatment ended: 18%
Doctor's advice 12   Doctor's advice: 14%
Side effects too severe 9   Side effects too severe: 11%
Personal research 7   Personal research: 8%
Not indicated 4   Not indicated: 5%
Expense 3   Expense: 4%

See all 83 patients who’ve stopped taking Diphenhydramine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Diphenhydramine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Diphenhydramine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Diphenhydramine

Always
 46 55%
Usually
 25 30%
Sometimes
 8 10%
Never
 4 5%

Burden

Difficulty being on treatment

Burden of Diphenhydramine

Very
 1 1%
Somewhat
 2 2%
A little
 9 11%
Not at all
 71 86%

Cost

Paid out of pocket

Cost of Diphenhydramine

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 1 2%
< $25
 52 98%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.