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Generic Name: 4-Aminopyridine (4-AP)

What is Fampridine-SR? Fampridine-SR, a sustained release formulation of 4-Aminopyridine, blocks potassium channels and prolongs action potentials thereby increasing transmitter release at the neuromuscular junction and elsewhere. It has been under study for spinal cord injuries and for Multiple Sclerosis.


Reasons Taken

9 patients in the community are taking or have taken Fampridine-SR.

Reason # Patients Percentage of patients
Other 5 55%
Mobility 2 22%
disease-related symptoms 1 11%
Stiffness/spasticity 1 11%

Dosages

Based on the patients currently taking Fampridine-SR.

Top 10 (Show all)

All (Show Top 10)

  0 mg Daily 0 other Daily 10 mg As needed 2 Daily 3.5 mg Daily 5 mg Daily 6 mg Daily 7.5 mg Daily 10 g Daily 10 mcg Daily 10 mg Daily 15 mg Daily 20 mg Daily 25 mg Daily 30 mg Daily 37.5 mg Daily 40 mg Daily 40 tbs. Daily 60 mg Daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 7 Number of Patients: 7 4 Number of Patients: 4 27 Number of Patients: 27 1 Number of Patients: 1 15 Number of Patients: 15 1 Number of Patients: 1 6 Number of Patients: 6 1 Number of Patients: 1 2 Number of Patients: 2  

Duration

How long current patients have been taking Fampridine-SR or how long patients were taking Fampridine-SR before stopping.

Currently taking Fampridine-SR

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
0
0
1
3
2

Stopped taking Fampridine-SR

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
1
0
Why Patients Stopped Taking Fampridine-SR (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 1 100% Other: 100%

Patient Reported Evaluations

Results from 2 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 50% 3
Moderate 50% 3

Other

Side-effects (as an overall problem)

Severe 8% 1
Moderate 8% 1
Mild 8% 1
None 77% 10

Top reported side-effects include:

Summary results are based on 2 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (1 of 2)

  • Lillian
    Sex: F
    Sensation: None
    Overall: None
    Cognition: mild
    Vision: none
    Speech: none
    Swallowing: mild
    Upper limb: mild
    Walking: moderate
    See profile
  • Lillian
  • by Lillian
    Aug 20, 2006
  • EfficacyMajor
  • Side-effectsNone
  • Other
Advice/Tips
How much it will improve the quality of their life.

See all evaluation results for Fampridine-SR



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