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Tizanidine Treatment Report
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Brand Names:
Sirdalud Retard, Tizanidine HCl, Zanaflex
Generic Name: Tizanidine
What is Tizanidine? Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.
See more information, including instructions, precautions, side effects, and interactions.
Reasons Taken
366 patients in the community are taking or have taken Tizanidine.
| Reason | # Patients | Percentage of patients |
|---|---|---|
| Stiffness/spasticity | 258 | 70% |
| Other | 26 | 7% |
| Pain | 19 | 5% |
| Muscle spasms, neck and shoulders | 6 | 1% |
| Muscle Spasms, feet and toes | 6 | 1% |
| disease-related symptoms | 5 | 1% |
| Slow my MS progress | 3 | <1% |
| Support another treatment | 2 | <1% |
| General health | 2 | <1% |
| Calf, feet cramps and muscle spasms | 2 | <1% |
| Depression | 2 | <1% |
| twitches and jerks | 1 | <1% |
| Muscle twitching (fasciculations) | 1 | <1% |
| Muscle cramping, spasms | 1 | <1% |
| Night-time leg spasms | 1 | <1% |
| Spasms, calves | 1 | <1% |
| MS Hug, or girdle-band sensation, stomach/chest/thighs | 1 | <1% |
| Spasms | 1 | <1% |
| Sexual dysfunction | 1 | <1% |
| Fatigue | 1 | <1% |
| Cramps, calf muscles | 1 | <1% |
| Don't know | 1 | <1% |
| Headaches/ Migraines | 1 | <1% |
| Burning sensation, soles of feet | 1 | <1% |
| 0 mg Daily | 2 mg As needed | 4 mg As needed | 10 mg As needed | 16 mg As needed | 20 mg As needed | 2 mg All the time (24/7) | 2 mg As needed | 2 mg Daily | 3 mg Daily | 4 mg As needed | 4 mg Daily | 5 mg Daily | 6 mg Daily | 8 mg Daily | 10 mg Daily | 12 mg As needed | 12 mg Daily | 14 mg Daily | 16 mg Daily | 18 mg Daily | 20 mg Daily | 24 mg Daily | 28 mg Daily | 30 mg Daily | 32 mg Daily | 40 mg Daily | 50 mg Daily | 100 mg Daily | 300 mg Daily | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
34
|
7
|
7
|
1
|
1
|
1
|
1
|
2
|
22
|
2
|
2
|
81
|
4
|
17
|
42
|
6
|
1
|
23
|
2
|
22
|
5
|
11
|
12
|
1
|
4
|
1
|
1
|
1
|
2
|
2
|
||
Duration
How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.
Currently taking Tizanidine
Stopped taking Tizanidine
Patient Reported Evaluations
Results from 24 patient evaluations. See the overall results and all individual evaluations.
Efficacy (Effect based on reason taken)
| Major | 35% | 8 |
|---|---|---|
| Moderate | 30% | 7 |
| Slight | 26% | 6 |
| None | 9% | 2 |
Stiffness/spasticity
Side-effects (as an overall problem)
| Severe | 8% | 2 |
|---|---|---|
| Moderate | 21% | 5 |
| Mild | 33% | 8 |
| None | 38% | 9 |
Top reported side-effects include: sleepy, Fatigue, makes me very sleepy
Summary results are based on 24 individual responses. For more information, see overall results for Adherence, Burden and Cost.
Individual Patient Reported Evaluations (2 of 24)
-
- feathers4me
- Sex: F
- Sensation: Severe
- Overall: Moderate
- Cognition: moderate
- Vision: moderate
- Speech: mild
- Swallowing: mild
- Upper limb: moderate
- Walking: severe
- See profile
-
by feathers4me
Aug 18, 2008
- EfficacyMajor
- Side-effectsModerate
- Stiffness/spasticity
- See full evaluation
-
0 helpful marks
-
- JesswithMS
- Sex: F
- Sensation: Moderate
- Overall: Moderate
- Cognition: moderate
- Vision: moderate
- Speech: moderate
- Swallowing: moderate
- Upper limb: moderate
- Walking: moderate
- See profile
-
by JesswithMS
Jun 10, 2007
- EfficacyMajor
- Side-effectsMild
- Stiffness/spasticity
- Advice/Tips
- Take as directed. I could never take it during the day, made me way too sleepy. Over time, I found that it lost its effect for me, but helped tremendously for the first few years.
- See full evaluation
-
0 helpful marks