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Home > Community Treatment Reports > Amitriptyline Treatment Report
What is Amitriptyline?

Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken
# of patients Efficacy
Major
Moderate
Slight
None
Can’t tell 		# of patients evaluated by
Pain 100 22
Other 51 13
Depression 36 4
Nerve pain 26 5
Insomnia 24 7
Migraine Headaches 14 2

See all 263 patients currently taking Amitriptyline

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe
7 12%
Moderate
12 20%
Mild
18 30%
None
23 38%

Most commonly reported side effects

dry mouth
11 31%
Hangover effect, next day
10 29%
Weight gain
10 29%
Excessive daytime sleepiness (somnolence)
10 29%
Grogginess
10 29%
quick changes of mood
6 17%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Amitriptyline. See all 26 dosages ►

  10mg/mL as needed 25mg as needed 50mg as needed daily 10 mg every other week 1 other daily 4 tbs. daily 5 mg daily 10 mg daily 12.5 mg daily 15 mg daily 20 mg daily 25 mg daily 30 mg daily 35 mg daily 37.5 mg daily 40 mg daily 50 mg daily 70 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily 225 mg daily 400 mg daily 600 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 54 Number of Patients: 54 1 Number of Patients: 1 1 Number of Patients: 1 16 Number of Patients: 16 48 Number of Patients: 48 14 Number of Patients: 14 2 Number of Patients: 2 1 Number of Patients: 1 5 Number of Patients: 5 45 Number of Patients: 45 1 Number of Patients: 1 16 Number of Patients: 16 34 Number of Patients: 34 4 Number of Patients: 4 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Amitriptyline (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
29 34% Did not seem to work: 34%
Side effects too severe
28 33% Side effects too severe: 33%
Other
19 22% Other: 22%
Doctor's advice
11 13% Doctor's advice: 13%
Course of treatment ended
7 8% Course of treatment ended: 8%
Not indicated
5 6% Not indicated: 6%
Personal research
2 2% Personal research: 2%
Expense
1 1% Expense: 1%

See all 81 patients who’ve stopped taking Amitriptyline

Duration See details about how long patients take this treatment ▼

Currently Taking Amitriptyline

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Amitriptyline

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always
41 68%
Usually
14 23%
Sometimes
4 7%
Never
1 2%

Burden

Difficulty being on treatment

Very
6 10%
Somewhat
2 3%
A little
7 12%
Not at all
45 75%

Cost

Paid out of pocket

$200+
0 0%
$100-199
1 2%
$50-99
1 2%
$25-49
0 0%
< $25
37 62%

See more information, including instructions, precautions, side effects, and interactions.

Report created on March 21, 2010.