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What is Zonisamide?

Zonisamide is an anticonvulsant drug that is used in combination with other medications to treat partial seizures in children over 16 years of age and adults with epilepsy. Off label it is used for Bipolar disorder.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Epilepsy 190 63 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Seizures (complex partial) 18 9 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Migraine headaches 13 2 Efficacy_moderate Efficacy_none
Seizures 8 0
Nerve pain (neuralgia) 7 1 Efficacy_major
Other 7 1 Efficacy_moderate

See all 257 patients currently taking Zonisamide

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Reported Side Effects

Side effects as an overall problem

Severe
 15
Moderate
 21
Mild
 20
None
 30

Commonly reported side effects, conditions, and hospitalizations associated with Zonisamide

Memory problems 5
Fatigue 3
Weight loss 3
Irritability 3
Chest tightness 3
Headaches 2
See all 55 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Zonisamide. See all 17 dosages ►

  25 mg daily 50 mg daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily 400 mg daily 500 mg daily 600 mg daily 700 mg daily
  4 Number of Patients: 4 11 Number of Patients: 11 34 Number of Patients: 34 7 Number of Patients: 7 56 Number of Patients: 56 50 Number of Patients: 50 46 Number of Patients: 46 28 Number of Patients: 28 20 Number of Patients: 20 6 Number of Patients: 6  

Reported Stop Reasons

Why Patients Stopped Taking Zonisamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 30   Side effects too severe: 46%
Did not seem to work 23   Did not seem to work: 35%
Doctor's advice 18   Doctor's advice: 28%
Other 5   Other: 8%
Expense 4   Expense: 6%
Course of treatment ended 4   Course of treatment ended: 6%
Personal research 3   Personal research: 5%
Change in health plan coverage 3   Change in health plan coverage: 5%
Not indicated 2   Not indicated: 3%

See all 63 patients who’ve stopped taking Zonisamide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Zonisamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Zonisamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Zonisamide

Always
 72 84%
Usually
 11 13%
Sometimes
 1 1%
Never
 2 2%

Burden

Difficulty being on treatment

Burden of Zonisamide

Very
 5 6%
Somewhat
 2 2%
A little
 14 16%
Not at all
 65 76%

Cost

Paid out of pocket

Cost of Zonisamide

$200+
 3 6%
$100-199
 0 0%
$50-99
 3 6%
$25-49
 10 20%
< $25
 35 69%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 12, 2012.