Select a community
MS
Find out more about the PatientsLikeMe
MS Community
Home > Community Treatment Reports > Methotrexate Treatment Report
What is Methotrexate?

Methotrexate is an antineoplastic drug used in the treatment of cancer. Also used as an antirheumatic for rheumatoid arthritis. Off label use in treatment of Crohn's disease and ectopic pregnancy. Experimental use in MS. It is given by mouth, by injection, via IV or intrathecally.

Side Effects

Side effects as an overall problem

Severe
1 9%
Moderate
1 9%
Mild
3 27%
None
6 55%

Most commonly reported side effects

Common cold
2 18%
hair loss
2 18%
Fatigue
2 18%
stomach upset
2 18%
flushing
2 18%
Infection
1 9%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Methotrexate. See all 16 dosages

  25 mg as needed 3.5g as needed 0.8 mcg weekly 3 mg weekly 3.5 mg weekly 7.5 mg weekly 10 mg weekly 12.5 mg weekly 15 mg weekly 2.5 mg daily 18 mg weekly 20 mg weekly 22.5 mg weekly 25 mg weekly 10 mg daily 1500 mg monthly
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 12 Number of Patients: 12 9 Number of Patients: 9 1 Number of Patients: 1 6 Number of Patients: 6 1 Number of Patients: 1 1 Number of Patients: 1 8 Number of Patients: 8 1 Number of Patients: 1 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Methotrexate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
9 38% Did not seem to work: 38%
Side effects too severe
5 21% Side effects too severe: 21%
Doctor's advice
4 17% Doctor's advice: 17%
Course of treatment ended
4 17% Course of treatment ended: 17%
Other
3 13% Other: 13%
Personal research
1 4% Personal research: 4%

See all 24 patients who’ve stopped taking Methotrexate

Currently Taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
4
1
5
1
14

Stopped Taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
0
1
3
6
11

Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Always
9 82%
Usually
1 9%
Sometimes
1 9%
Never
0 0%

Burden

Difficulty being on treatment

Very
0 0%
Somewhat
3 27%
A little
2 18%
Not at all
6 55%

Cost

Paid out of pocket

$200+
0 0%
$100-199
1 9%
$50-99
0 0%
$25-49
1 9%
< $25
4 36%

See more information, including instructions, precautions, side effects, and interactions.

Report created on November 23, 2009.