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What is Methotrexate? Methotrexate is an antineoplastic drug used in the treatment of cancer. Also used as an antirheumatic for rheumatoid arthritis. Off label use in treatment of Crohn's disease and ectopic pregnancy. Experimental use in MS. It is given by mouth, by injection, via IV or intrathecally.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

54 patients in the community are taking or have taken Methotrexate.

Reason # Patients Percentage of patients
Slow my MS progress 35 64%
Other 12 22%
Pain 4 7%
Depression 1 1%

Dosages

Based on the patients currently taking Methotrexate.

Top 10 (Show all)

All (Show Top 10)

  0 As needed 3.5 g As needed 3 mg Weekly 3.5 mg Weekly 7.5 mg Weekly 10 mg Weekly 15 mg Weekly 18 mg Weekly 20 mg Weekly 25 mg Weekly 10 mg Daily 25 mg Daily 1500 mg Monthly
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 5 Number of Patients: 5 4 Number of Patients: 4 1 Number of Patients: 1 4 Number of Patients: 4 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking Methotrexate or how long patients were taking Methotrexate before stopping.

Currently taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
0
3
3
3
9

Stopped taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
0
1
3
4
6
Why Patients Stopped Taking Methotrexate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 5 33% Did not seem to work: 33%
Side effects too severe 4 27% Side effects too severe: 27%
Doctor's advice 3 20% Doctor's advice: 20%
Course of treatment ended 3 20% Course of treatment ended: 20%
Personal research 1 7% Personal research: 7%
Other 1 7% Other: 7%

Patient Reported Evaluations

Results from 4 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Can't tell 100% 2

Slow my MS progress

Side-effects (as an overall problem)

Severe 0% 0
Moderate 25% 1
Mild 50% 2
None 25% 1

Top reported side-effects include: stomach upset, hair loss, colds

Summary results are based on 4 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (1 of 4)

  • shuffles
    Sex: F
    Sensation: Severe
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: none
    Upper limb: severe
    Walking: moderate
  • shuffles
  • by shuffles
    Sep 09, 2008
  • EfficacyMajor
  • Side-effectsNone
  • Pain
Advice/Tips
this medication works well combined with other medication for rheamatoid arthritis.

See all evaluation results for Methotrexate



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