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What is Cyclophosphamide?

Cyclophosphamide is a nitrogen mustard alkylating agent that is used to treat various types of cancer. It is also used to prevent transplant rejection and autoimmune disorders; rheumatoid disorders, myasthenia gravis, nephrotic syndrome, multiple scelrosis, lupus and certain blood disorders.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
MS (Multiple Sclerosis) 50 27 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 8 3 Efficacy_moderate Efficacy_none Efficacy_cant_tell
Improve mobility 5 1 Efficacy_moderate
Lupus Nephritis 4 1 Efficacy_major
Wegener's granulomatosis 4 1 Efficacy_cant_tell
Walking problems 4 2 Efficacy_major Efficacy_slight

See all 33 patients currently taking Cyclophosphamide

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Reported Side Effects

Side effects as an overall problem

Severe
 7
Moderate
 12
Mild
 13
None
 5

Commonly reported side effects, conditions, and hospitalizations associated with Cyclophosphamide

Nausea 12
Hair loss (alopecia) 11
Fatigue 8
Constipation 6
Vomiting 4
Headaches 3
See all 25 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Cyclophosphamide. See all 19 dosages ►

  monthly 1 g monthly 100 mg monthly 200 mg monthly 700 mL monthly 25 mg daily 800 mg monthly 1,000 mg monthly 50 mg daily 100 mg daily
  3 Number of Patients: 3 8 Number of Patients: 8 2 Number of Patients: 2 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Cyclophosphamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 40   Course of treatment ended: 57%
Did not seem to work 19   Did not seem to work: 27%
Doctor's advice 14   Doctor's advice: 20%
Side effects too severe 14   Side effects too severe: 20%
Other 6   Other: 9%
Personal research 3   Personal research: 4%

See all 70 patients who’ve stopped taking Cyclophosphamide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Cyclophosphamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Cyclophosphamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Cyclophosphamide

Always
 36 97%
Usually
 0 0%
Sometimes
 0 0%
Never
 1 3%

Burden

Difficulty being on treatment

Burden of Cyclophosphamide

Very
 8 22%
Somewhat
 14 38%
A little
 6 16%
Not at all
 9 24%

Cost

Paid out of pocket

Cost of Cyclophosphamide

$200+
 2 9%
$100-199
 0 0%
$50-99
 2 9%
$25-49
 1 5%
< $25
 16 73%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.