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Brand Names: Tysabri

What is Natalizumab? Natalizumab is a monoclonal antibody given by infusion and used in the treatment of MS and Crohn's disease. It has been shown to slow progression and reduce relapses in MS. It is currently sold under the brand name Tysabri.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

490 patients in the community are taking or have taken Natalizumab.

Reason # Patients Percentage of patients
Slow my MS progress 393 80%
Other 26 5%
General health 10 2%
Stiffness/spasticity 6 1%
Fatigue 3 <1%
Don't know 2 <1%
disease-related symptoms 2 <1%
no energy 1 <1%
Pain 1 <1%
Weakness in legs 1 <1%
Sensation 1 <1%
Mobility 1 <1%
transfering 1 <1%

Dosages

Based on the patients currently taking Natalizumab.

Top 10 (Show all)

All (Show Top 10)

  0 g Monthly 0 mg Monthly 0 other Monthly 0 Monthly 300 mg As needed 300 mg Monthly 1 g Monthly 1 mg Monthly 1 Monthly 4 mg Monthly 5 mg Monthly 15 mg Monthly 20 mg Monthly 25 mg Monthly 30 mg Monthly 50 mg Monthly 100 mg Monthly 200 mg Monthly 300 mg Monthly 1000 mg Monthly 300 mg Daily
  1 Number of Patients: 1 161 Number of Patients: 161 1 Number of Patients: 1 25 Number of Patients: 25 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 3 Number of Patients: 3 4 Number of Patients: 4 195 Number of Patients: 195 1 Number of Patients: 1 10 Number of Patients: 10  

Duration

How long current patients have been taking Natalizumab or how long patients were taking Natalizumab before stopping.

Currently taking Natalizumab

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
12
24
39
75
88
32

Stopped taking Natalizumab

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
6
13
16
10
7
2
Why Patients Stopped Taking Natalizumab (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 22 39% Doctor's advice: 39%
Other 21 38% Other: 38%
Side effects too severe 18 32% Side effects too severe: 32%
Did not seem to work 15 27% Did not seem to work: 27%
Expense 3 5% Expense: 5%
Course of treatment ended 2 4% Course of treatment ended: 4%
Personal research 1 2% Personal research: 2%

Patient Reported Evaluations

Results from 52 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 21% 10
Moderate 29% 14
Slight 15% 7
None 13% 6
Can't tell 23% 11

Slow my MS progress

Side-effects (as an overall problem)

Severe 6% 3
Moderate 2% 1
Mild 42% 22
None 50% 26

Top reported side-effects include: tiredness, mild headache, Headaches

Summary results are based on 52 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 52)

  • LadyMac
    Sex: F
    Sensation: Moderate
    Overall: Mild
    Cognition: none
    Vision: moderate
    Speech: none
    Swallowing: mild
    Upper limb: moderate
    Walking: moderate
  • LadyMac
  • by LadyMac
    Aug 18, 2008
  • EfficacyCan't tell
  • Side-effectsNone
  • Slow my MS progress
Advice/Tips
Just be positive about the drug, that it's for you and what you need and want. Positive thinking can help more then one thinks. I'm looking forward to my next infusion next month. August '08 was my first infusion and I was happy with the TOUCH program. Was a very relaxing experience.

  • cureseeker
    Sex: F
    Sensation: Moderate
    Overall: Mild
    Cognition: moderate
    Vision: moderate
    Speech: none
    Swallowing: none
    Upper limb: none
    Walking: moderate
  • by cureseeker
    Aug 18, 2008
  • EfficacySlight
  • Side-effectsMild
  • Slow my MS progress

See all evaluation results for Natalizumab



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