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What is Divalproex sodium?

Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Epilepsy 399 128 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 121 48 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar Disorder 117 43 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Migraine headaches 48 13 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Bipolar manic episodes 43 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar I Disorder 31 14 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell

See all 665 patients currently taking Divalproex sodium

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Reported Side Effects

Side effects as an overall problem

Severe
 86
Moderate
 86
Mild
 85
None
 55

Commonly reported side effects, conditions, and hospitalizations associated with Divalproex sodium

Weight gain 81
Hair loss 31
Fatigue 26
Drowsiness 23
Nausea 11
Tremor 10
See all 167 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Divalproex sodium. See all 42 dosages ►

  125 mg daily 250 mg daily 500 mg daily 750 mg daily 1,000 mg daily 1,250 mg daily 1,500 mg daily 1,750 mg daily 2,000 mg daily 2,500 mg daily
  17 Number of Patients: 17 55 Number of Patients: 55 137 Number of Patients: 137 64 Number of Patients: 64 187 Number of Patients: 187 14 Number of Patients: 14 95 Number of Patients: 95 10 Number of Patients: 10 67 Number of Patients: 67 12 Number of Patients: 12  

Reported Stop Reasons

Why Patients Stopped Taking Divalproex sodium (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 183   Side effects too severe: 52%
Did not seem to work 131   Did not seem to work: 37%
Doctor's advice 89   Doctor's advice: 25%
Other 57   Other: 16%
Personal research 22   Personal research: 6%
Expense 19   Expense: 5%
Course of treatment ended 12   Course of treatment ended: 3%
Not indicated 6   Not indicated: 2%
Change in health plan coverage 3   Change in health plan coverage: 1%

See all 339 patients who’ve stopped taking Divalproex sodium

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Divalproex sodium

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Divalproex sodium

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Divalproex sodium

Always
 257 82%
Usually
 41 13%
Sometimes
 8 3%
Never
 6 2%

Burden

Difficulty being on treatment

Burden of Divalproex sodium

Very
 27 9%
Somewhat
 58 19%
A little
 64 21%
Not at all
 163 52%

Cost

Paid out of pocket

Cost of Divalproex sodium

$200+
 13 7%
$100-199
 9 5%
$50-99
 21 11%
$25-49
 36 18%
< $25
 114 58%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.