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What is Methylfolate (l-methylfolate)?

Methylfolate, or l-methylfolate, is the active form of folate in the body. Folate is necessary for formation of numerous coenzymes in many metabolic systems.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Increase effect of another treatment 33 10 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 24 8 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 14 2 Efficacy_moderate Efficacy_cant_tell
Major Depressive Disorder 7 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
depression, might help fibro? 5 2 Efficacy_moderate
Other 4 0

See all 106 patients currently taking Methylfolate (l-methylfolate)

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Reported Side Effects

Side effects as an overall problem

Severe
1
Moderate
1
Mild
3
None
36

Commonly reported side effects, conditions, and hospitalizations associated with Methylfolate (l-methylfolate)

Sleepiness 2
Weight gain 1
Dizziness 1
Possible cause of hives 1
Dysphoric mania 1
Generalized Anxiety Disorder 1
See all 7 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Methylfolate (l-methylfolate). See all 12 dosages

  daily 1 tbs. daily 1 mg daily 1.75 mg daily 2 mg daily 2 daily 5 mg daily 7.5 mg daily 15 mg daily 100 mg daily
  23 Number of Patients: 23 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 55 Number of Patients: 55 16 Number of Patients: 16 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Methylfolate (l-methylfolate) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 17   Did not seem to work: 47%
Expense 10   Expense: 28%
Other 9   Other: 25%
Course of treatment ended 5   Course of treatment ended: 14%
Doctor's advice 3   Doctor's advice: 8%
Side effects too severe 2   Side effects too severe: 6%
Change in health plan coverage 1   Change in health plan coverage: 3%

See all 35 patients who’ve stopped taking Methylfolate (l-methylfolate)

Currently Taking Methylfolate (l-methylfolate)

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Methylfolate (l-methylfolate)

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Methylfolate (l-methylfolate)

Always
34 83%
Usually
6 15%
Sometimes
0 0%
Never
1 2%

Burden

Difficulty being on treatment

Burden of Methylfolate (l-methylfolate)

Very
1 2%
Somewhat
1 2%
A little
9 22%
Not at all
30 73%

Cost

Paid out of pocket

Cost of Methylfolate (l-methylfolate)

$200+
0 0%
$100-199
2 6%
$50-99
9 26%
$25-49
8 24%
< $25
15 44%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.