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What is Cyclosporine?

Cyclosporin is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It has been studied in transplants of skin, heart, kidney, lung, pancreas, bone marrow and small intestine.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Prevent organ rejection 152 14 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Transplant rejection prevention 86 24 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Psoriatic Arthritis 7 0
Kidney Transplant 5 0
Psoriasis 4 1 Efficacy_major
Kidney Transplant 4 1 Efficacy_major

See all 231 patients currently taking Cyclosporine

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Reported Side Effects

Side effects as an overall problem

Severe
4
Moderate
26
Mild
8
None
5

Commonly reported side effects, conditions, and hospitalizations associated with Cyclosporine

Hair growth 7
Elevated blood pressure 3
Hair growth increased 3
Night cramps in legs and feet 2
Skin cancer 2
Facial hair excessive 2
See all 64 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Cyclosporine. See all 39 dosages

  25 mg daily 50 mg daily 75 mg daily 100 mg daily 125 mg daily 150 mg daily 200 mg daily 250 mg daily 300 mg daily 400 mg daily
  14 Number of Patients: 14 15 Number of Patients: 15 11 Number of Patients: 11 33 Number of Patients: 33 8 Number of Patients: 8 31 Number of Patients: 31 60 Number of Patients: 60 17 Number of Patients: 17 15 Number of Patients: 15 8 Number of Patients: 8  

Reported Stop Reasons

Why Patients Stopped Taking Cyclosporine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 37   Doctor's advice: 51%
Side effects too severe 22   Side effects too severe: 30%
Did not seem to work 15   Did not seem to work: 21%
Other 9   Other: 12%
Course of treatment ended 6   Course of treatment ended: 8%
Personal research 3   Personal research: 4%
Expense 1   Expense: 1%
Change in health plan coverage 1   Change in health plan coverage: 1%
Not indicated 1   Not indicated: 1%

See all 69 patients who’ve stopped taking Cyclosporine

Currently Taking Cyclosporine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Cyclosporine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Cyclosporine

Always
36 84%
Usually
7 16%
Sometimes
0 0%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Cyclosporine

Very
1 2%
Somewhat
4 9%
A little
13 30%
Not at all
25 58%

Cost

Paid out of pocket

Cost of Cyclosporine

$200+
5 20%
$100-199
3 12%
$50-99
4 16%
$25-49
2 8%
< $25
11 44%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.