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What is Metformin?

Metformin an antidiabetic agent used for the management of type 2 diabetes mellitus (noninsulin dependent, NIDDM) as monotherapy when hyperglycemia (high blood sugar) cannot be managed with diet and exercise alone.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Diabetes Type 2 847 139 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
PCOS (Polycystic Ovary Syndrome) 89 19 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Other 76 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Diabetes Mellitus 29 4 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Polycystic Ovary Syndrome (PCOS) 19 7 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Elevated blood sugar (hyperglycemia) 18 8 Efficacy_major Efficacy_slight Efficacy_cant_tell

See all 1049 patients currently taking Metformin

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Reported Side Effects

Side effects as an overall problem

Severe
29
Moderate
38
Mild
53
None
82

Commonly reported side effects, conditions, and hospitalizations associated with Metformin

Diarrhea 40
Nausea 14
Stomach pain 7
Loose stools 6
Fatigue 6
Stomach upset 5
See all 80 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Metformin. See all 47 dosages

  500 mg/5 mL daily 500 mg daily 850 mg daily 1,000 mg daily 2 x 500 mg/5 mL daily 3 x 500 mg/5 mL daily 1,500 mg daily 1,700 mg daily 2,000 mg daily 4 x 500 mg/5 mL daily
  48 Number of Patients: 48 177 Number of Patients: 177 22 Number of Patients: 22 297 Number of Patients: 297 53 Number of Patients: 53 18 Number of Patients: 18 74 Number of Patients: 74 26 Number of Patients: 26 292 Number of Patients: 292 23 Number of Patients: 23  

Reported Stop Reasons

Why Patients Stopped Taking Metformin (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 63   Doctor's advice: 34%
Side effects too severe 63   Side effects too severe: 34%
Did not seem to work 38   Did not seem to work: 21%
Other 31   Other: 17%
Course of treatment ended 18   Course of treatment ended: 10%
Expense 7   Expense: 4%
Personal research 6   Personal research: 3%
Change in health plan coverage 6   Change in health plan coverage: 3%
Not indicated 2   Not indicated: 1%

See all 173 patients who’ve stopped taking Metformin

Currently Taking Metformin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Metformin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Metformin

Always
139 69%
Usually
39 19%
Sometimes
8 4%
Never
16 8%

Burden

Difficulty being on treatment

Burden of Metformin

Very
13 6%
Somewhat
19 9%
A little
41 20%
Not at all
129 64%

Cost

Paid out of pocket

Cost of Metformin

$200+
3 2%
$100-199
1 1%
$50-99
1 1%
$25-49
6 5%
< $25
117 91%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.