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What is Primidone?

Primidone is a barbituate anticonvulsant used for the management of grand mal, psychomotor, and focal seizures. Off label it is used for benign familial tremor, also known as essential tremor.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Essential Tremor 24 9 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Epilepsy 24 11 Efficacy_major Efficacy_moderate Efficacy_none
Tremor 21 5 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Seizures (grand mal or tonic-clonic) 11 3 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Other 10 2 Efficacy_major Efficacy_moderate
Parkinson's Disease 6 2 Efficacy_moderate Efficacy_cant_tell

See all 95 patients currently taking Primidone

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Reported Side Effects

Side effects as an overall problem

Severe
 7
Moderate
 8
Mild
 13
None
 11

Commonly reported side effects, conditions, and hospitalizations associated with Primidone

Dizziness 6
Grogginess 5
Fatigue 5
Somnolence 2
Tiredness 1
Sleepiness 1
See all 22 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Primidone. See all 26 dosages ►

  50 mg daily 100 mg daily 150 mg daily 200 mg daily 250 mg/5 mL daily 250 mg daily 300 mg daily 500 mg daily 3 x 250 mg/5 mL daily 750 mg daily
  20 Number of Patients: 20 10 Number of Patients: 10 7 Number of Patients: 7 5 Number of Patients: 5 5 Number of Patients: 5 4 Number of Patients: 4 6 Number of Patients: 6 13 Number of Patients: 13 4 Number of Patients: 4 6 Number of Patients: 6  

Reported Stop Reasons

Why Patients Stopped Taking Primidone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 15   Side effects too severe: 48%
Did not seem to work 14   Did not seem to work: 45%
Doctor's advice 9   Doctor's advice: 29%
Other 4   Other: 13%
Personal research 2   Personal research: 6%
Course of treatment ended 1   Course of treatment ended: 3%

See all 31 patients who’ve stopped taking Primidone

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Primidone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Primidone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Primidone

Always
 35 90%
Usually
 2 5%
Sometimes
 2 5%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Primidone

Very
 2 5%
Somewhat
 3 8%
A little
 10 26%
Not at all
 24 62%

Cost

Paid out of pocket

Cost of Primidone

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 4%
$25-49
 2 7%
< $25
 25 89%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.