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What is Pyridostigmine?

Pyridostigmine is an acetylcholinesterase inhibitor used for the symptomatic treatment of myaesthenia gravis and as an antidote for nondepolarizing neuromuscular blockers.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Myasthenia Gravis 25 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Other 10 3 Efficacy_major Efficacy_moderate Efficacy_slight
Fatigue 6 2 Efficacy_moderate Efficacy_none
ALS (Amyotrophic Lateral Sclerosis) 4 0
Lambert-Eaton Myasthenic Syndrome 3 0
Dysautonomia 2 1 Efficacy_slight

See all 45 patients currently taking Pyridostigmine

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
5
Mild
3
None
7

Commonly reported side effects, conditions, and hospitalizations associated with Pyridostigmine

Diarrhea 2
Nausea 1
Memory problems 1
Muscle twitching (fasciculations) 1
Woozy 1
Excessive tearing eyes 1
See all 8 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Pyridostigmine. See all 19 dosages

  60mg as needed 60 mg daily 80 mg daily 90 mg daily 120 mg daily 180 mg daily 240 mg daily 300 mg daily 360 mg daily 480 mg daily
  2 Number of Patients: 2 8 Number of Patients: 8 1 Number of Patients: 1 5 Number of Patients: 5 8 Number of Patients: 8 7 Number of Patients: 7 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Pyridostigmine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 8   Did not seem to work: 50%
Doctor's advice 5   Doctor's advice: 31%
Side effects too severe 3   Side effects too severe: 19%
Other 3   Other: 19%
Course of treatment ended 1   Course of treatment ended: 6%

See all 15 patients who’ve stopped taking Pyridostigmine

Currently Taking Pyridostigmine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Pyridostigmine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Pyridostigmine

Always
9 60%
Usually
5 33%
Sometimes
1 7%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Pyridostigmine

Very
0 0%
Somewhat
1 7%
A little
5 33%
Not at all
9 60%

Cost

Paid out of pocket

Cost of Pyridostigmine

$200+
0 0%
$100-199
0 0%
$50-99
1 17%
$25-49
3 50%
< $25
2 33%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.