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What is Infliximab?

Infliximab is a monoclonal antibody used in the treatment of rheumatoid arthritis; Crohn's disease; psoriatic arthritis; chronic severe psoriasis; and ankylosing spondylitis. Off label used for acute graft-versus-host disease (GVHD) and juvenile rheumatoid arthritis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
RA (Rheumatoid Arthritis) 25 6 Efficacy_major Efficacy_moderate
Crohn's Disease 22 8 Efficacy_major Efficacy_moderate Efficacy_slight
Psoriatic arthritis 13 1 Efficacy_major
Ankylosing Spondylitis 7 2 Efficacy_moderate Efficacy_cant_tell
Rheumatoid Arthritis 5 2 Efficacy_major Efficacy_slight
Ulcerative colitis 4 2 Efficacy_cant_tell

See all 57 patients currently taking Infliximab

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Reported Side Effects

Side effects as an overall problem

Severe
 2
Moderate
 3
Mild
 10
None
 6

Commonly reported side effects, conditions, and hospitalizations associated with Infliximab

Joint pain 3
Headaches 2
Fatigue 2
Lumps and bumps 1
Allergic reaction 1
Sinus infection 1
See all 13 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Infliximab. See all 38 dosages ►

  100 mg every 3 months 100 mg every 8 weeks 100 mg every 6 weeks 100 mg monthly 436 mg every 3 months 100 mg every other week 300 mg monthly 400 mg monthly 500 mg monthly 800 mg monthly
  7 Number of Patients: 7 3 Number of Patients: 3 2 Number of Patients: 2 4 Number of Patients: 4 2 Number of Patients: 2 2 Number of Patients: 2 4 Number of Patients: 4 3 Number of Patients: 3 3 Number of Patients: 3 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Infliximab (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 8   Did not seem to work: 27%
Side effects too severe 8   Side effects too severe: 27%
Other 8   Other: 27%
Doctor's advice 6   Doctor's advice: 20%
Expense 5   Expense: 17%
Not indicated 4   Not indicated: 13%
Change in health plan coverage 1   Change in health plan coverage: 3%
Personal research 1   Personal research: 3%

See all 28 patients who’ve stopped taking Infliximab

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Infliximab

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Infliximab

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Infliximab

Always
 20 95%
Usually
 0 0%
Sometimes
 1 5%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Infliximab

Very
 1 5%
Somewhat
 10 48%
A little
 6 29%
Not at all
 4 19%

Cost

Paid out of pocket

Cost of Infliximab

$200+
 5 45%
$100-199
 1 9%
$50-99
 1 9%
$25-49
 1 9%
< $25
 3 27%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.